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technetium and radioiodine uptakes in a typical euthyroid individual are
seen in Fig. 6.
As expected the technetium uptake is very rapid in the first
ten minutes (T1/2-5 min.) and then levels off.
The Lodine uptake 1s also
very rapid in this same period of time with the level of uptake somewhat
higher than the technetium uptake.
It too, levels off to a slope
The second component of
approaching zero in the time scale of the graph.
this curve can not be accurately determined because it has a T1/2 of about
6 - 10 hours and recording was only for 1/2 hour.
Several interesting examples have been noted already in our short
series.
One patient (Fig. 7) with hyperthyroidism confirmed by several
in-vitro studies had a technetium curve which was distinctly abnormal
(maximum uptake 5.1%) while the radioiodine uptake during the first half
hour was consistently lower than the technetium uptake.
The twenty-four
hour radioiodine uptake in this patient was only 24.9%.
A more typical
example of hyperthyroidism is patient
(Fig. 8) where the iodine uptake
was always higher than the technetium uptake with both being high.
Another interesting varient is the data on patient
(Fig. 9),
thought to have Hashimotos' thyroiditis although autoantibodies were
negative and the serum thyroxine level was normal.
uptake was elevated (47.6%).
The 24 hour radioiodine
The curves show an early peak of technetium
uptake at about 12 minutes and then a decline.
The radioiodine uptake
was consistently high, reahing 9.1% at 30 minutes.
The study fs continuing and it is hoped to learn more about the early
thyroid uptake of iodine and technetium.
We are also obtaining close-up
scintiphotos of the thyroid at 30 minutes with technetium, and at 30 minutes
and 24 hours with radioiodine.
It should be interesting to see any
correspondance between the 30 minute images of the two radiopharmaceuticals
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