tion of the neck appeared to be definitely increased at the site of previous lesions. However, Httle thickening, if any, was apparent and the skin appeared otherwise normal. It is noteworthy that none of the neck lesions showed depigmentation. Small areas of hyperpigmentation persisted also at the site of two axillary, four antecubital fossae, one arm, and one back lesion. In contrast to the neck and other lesions mentioned, the deepest foot lesions showed no hyperpigmentation but, on the contrary, persisting depigmentation. Plates 3 and 4 show deeper foot lesions early andat 6 months post-exposure. The skin texture in these depigmented le- sions appeared essentially normal on a gross scale. However, pictures magnified 20 times showedthat there was scattered, blotchy, faded pigmentation with some slight atrophy (fatten- ing of skin ridges). Depigmented foot lesions were observed in six cases. One antecubital fossae lesion also showed a small area of depigmentation. The persistent lesion of the ear, noted in the initial examination, had gradually healed with considerable scarring and atrophy and some scaling cof the epidermis. Plates 5, 6, and 7 show this lesion early and at 6 months post-exposure. Telangiectatic vessels can also be seen in Plate 7 (magnified 20 times). In every case, there appeared to be a complete regrowth of hair, with normal color, texture, and distribution. Plates 5, 6, 8, and 9 show epilation and regrowth of hair. The bluish-brown pigmentation of the nails, noted in most of the Marshallese in the initial examinations, had disappeared, apparently with growth of the nails, in all but three cases. The pigment in these indiv.tuals remained at the distal end of the nail (Plate 10). It was evident in these cases that the pigment was not in the nail plate but between it and the nail bed, closely adherent to the underside of the aai!. Biopsies showed some residual damage to the epidermis, as well as to the dermis. In the epidermis the following changes were present: (1) focal atrophy of the stratum granulosum; (2) slight focal pigmentary disturbances in cells of the basal layers; (3) slight-to-moderate hyperheratinization; and (4) in sor-e cases persistent, but minimum cellular, changes as manifested by the presence of paranuclear cytoplasmic halos and slight disturbances in polarity of epithelial cells in the basal capillary projections. In the dermis a slight-to-moderate degree of telangiectasis was evident. Some of these changes are shown in Plates 11 and 12. NOTE Color plates ,Plates 1 through 12) numbered with letters a, 6, c, and d are considered to be pages 17 through 24. 16 ™~