(1) Movement in the laboratory is from "cold" to "hot" areas passing through intermediate zones (2) Helps prevent spread of contamination (3) Excludes all but those persons most directly concerned from dangerous areas (4) Air flow in building design from positive pressure halls to offices to still lower pressure laboratories Concentrate radiation zones (1) Control radiation by total enclosure of the radioactive material (a) Dry boxes (ob) Hot cells Total control assures personnel protection and minimizing contamination

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