Effect of radiation on tissues and organs Tissues and organs basically collections of cells Individual cells reflect the degree of damage done Cells that make up the different tissues and organs of the body differ in their response to radiation (1) Intestines (2) Blood-forming organs Results of radiation damage to organs (1) Increase or decrease in organ's products (2) Alteration in organ's growth (3) Death of the tissue or organ Radiation exposure a. Type of radiation a factor in biological effects (dose for dose, radiation of high specific ionization produces greater biological effects than radiation of low specific ionization) Type of dose as factor in biological effects (1) Acute dose (generally, single exposure to twenty-five roentgens or more) (2) Chronic dose (absorption of relatively small amounts of radiation daily over a long period of time) (3) Body's response to irradiation depends on the fraction of the whole body volume exposed (a) Whole body irradiation (0) Localized irradiation

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