Table 20 Growth and Thyroid Studies in Subjects With Thyroid Abnormalities Neck '*7I at 4 hr," % of dose Growth Subject No. and sex Thyroid abnormality 3M Atrophy 3 M_ 17 Year tested Chronological age, yr Skeletal ranking, yr Statural ranking,” percentile Pre TSH Post TSH Serum iodine, ue% PBI 1965 13 3 <10 Atrophy 1965 13 D2 <10 F Nodular 1965 15 13%2 90 6.8('64) 21 F Nodular 1965 15 15 10-25 8.1(°64) 69 F Nodular 1965* 16 16 2 M Nodular 1965 13 20 M Nodular 1965 72, F Nodular goiter 42 F 61 goiter goiter goiter 1966 1966 1966 1966° 1966° 08 1.9 0.8 3.1 <0.5 440 5.7 1.7 125 7.1 19 Adult 25-50 1965 18 17%2 >90 Nodular goiter 1965 1966 15 13%2 10 F Nodular 1965 20 Adult 50-75 54 M_ Nodular goiter 1965 1966 13 13 90 19 M_ Nodular goiter 1965 1966* 17 15%2 10 36 M_ Nodular 1965 19 18 75 4.1 33 F Nodular goiter 1965 1966 13 13%2 >90 65 F Nodular goiter 1965 1966 13 10%2 <10 59 F Solitary nodule 1965 1966 35 64 F Carcinoma 1965 19664 31 40 M_ Solitary nodule 1965 40 goiter goiter goiter 1966 1966 119 372 1.3 18 159 <0.5 25-50 19667 >120 248 1.8 6.5 1.0 TSH," ng/ml 1.8 112 goiter - >90 1.4 3.2 8 T,I Serum (29) (23) 7.9 4.2 (31) (3h) 65 4.2 3.2 2.6 9.6 26.6 5.3 (15) (24) 3.7 4.6 12°10) (24) 7.9 4.9 8.3 5.0 4.3 <3 <1 3.9 3.3 <7 4.2 4.3 <17 3.8 73 197 6.6 235 19 (16) (24) 7.0 59 17 (9) (14) 4.9 31 2.1 1.9 7°(20) (38) 8.2 8.6 5.3 4.8 (19) (28) 8.6 4.9 3.4 2.0 : <17 10.3 @Values in parentheses obtained at BNL. >Relative statural growth expressed as percentile ranking compared with growth curves of unexposed Marshallese children. ‘Assays in 1965 could not detect levels below 3 nanograms/ml. Seven unexposed children in the same age group had <3 ng/ml. Assays in 1966 could not detect levels below 17 ng/ml. Three exposed children without thyroid disease (Nos. 6, 8, and 32) had <17 ng/ml. Two children exposed tn utero (Nos. 84 and 86) and two unexposed children had <17 ng/ml. The 1966 levels were obtained about 3 weeks after cessation of thyroxine therapy, the 1965 levels. betore therapy wasinstituted. We are grateful to Dr. William Odell at the National Institutes of Health for carrying cut these assays. ‘Post partial thyroidectomy. “While taking thyroxine.