showing minimum count at 4th- 8th week.
5 cases revealed a count
of less than 2,000/mm?, 13 less than 3,000 and 5 less than 4,000,
In one case, the leukocyte level depressed to 800.
<A correlation
was found between these minimum count and the externally irradiated
yammia doses of cach individual,
Ac first lymphopenia was noticed
and then neutropenia became marked.
proved.
Since 8th week recovery was
In many cases remarkable cosinophilia was observed at
that tinke.,
In some cases immature neutrophils appeared in peripheral
hlood slightly.
b.
Erythrocytes :
In severe cases slight ancmia was observed,
uwccompanied by the depression of reticulocytes.
were higher than 1.0,
Color indices
The Price-Jones curves of erythrocytes
diamcter were displaced to the right of normal one at first, which
returned to almost normal after one year.
c.
Platelets : Platelets counts showed increasing depression,
reaching munimum at the 4th- 7th week (15,000 - 100,000/mm?}.
Slight coavulation disturbances observed in a few cases,
d.
Bone marrow:
In severe cases bone marrow was highly
hypoplastic at the critical stape, which changed to hypoplastic and
turned into almost normoplastic.,
after a year.
Recovery was not complete even
At the recovery stage coexistence of hypoplastic area
and hypernlastic area was observed in histolovical sections.
¢,
Morphological abnormahties :
Several morphological
abnormalities, c.u. abnormal granules in lymphocytes or neutrophils,
vacuoles in various leukocytes and megakaryocytes, giant nuclei and
hyperseumentation of neutrophils, binuclear lymphocytes, abnormal
mitosis of erythroblasts etc. were observed far about one year,
especially at the critical and recovery stage.
A dittle inerease of
“anitoatically connected ahnormiatities" was found in bone marrow
smears of a few cases after 10 years.
f{.
Recovery :
The cumulative dist:ibution curves of numbers of
leukocytes, erythrocytes and plateicts displaced to the left of normal
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