‘
Tna atrophy of the lymphatic systea may have beon due to radiation
sictness end wo plen to study this mitter very carcfully.
aAlthoush we
have cxanined only the lymph nodes of the mosentery, the neck, and the
armpit, wo found that in the mesentory the lymphatie sinus was considercbly expanded and the endothelial cells wore prominently proliferated;
nobilization was observed, Proliferated endothelial cells wore goraan~
diging the nuclei in which red and wnite corpuscles had bean destroyed.
Owing to proliferaticn, tho original ly-phatie tissue was rather
atrophied, resulting in a strveture in which the cortex was difficult
to distinguish and the ecnter +23 hrrdly visible. The lymph nxies of
tha arnspit were rother atropnic and the certex contained glassy deposits. Tre lymph nodes of the neck showed atrophy, endothelial
deseneration, and developzent of polynuclear giant cells, It wes very
difficult to prasp the nesning of these findings; but I shall study
them further,
The testicles apposred sonewhat atropiied to the naked eye. Histo~
lorically spoaking, sperz2togonia were scarcely in evidence and mature
spermatozoa were not seen. Tons besal mexbrane of the sperczatic
tubules g2i3 prominently swollen. On tha other hand Sertolifs cells
and Leydig's eclls were observed vwithout difficulty. Deseneration in
the testes, tostther idth henstopoletic dyufimetion, {5 very highly
etiraecteristic of ridietion sicirris.
Cther wsatters waich I an now stulying and which aro not recdy for
totcyts diseussion will ba furmishrd to tha t'sdical Croup of the
Cawicll on Counter:essurca for further guidenca and cdvice.
oe ary
Thus far, I have discussed the pathological changes in Ir.
c2s0; now let ns susmarice,
First of all, the changes arocaused by
rediation sickness. I believe they occurred in two ways: fren cx=
ternal radiation and from internal radiations. One would suppose that
ths degeneration fron beta radiation bums would appear in the ecto~
derzal skin or the nesoderaal or scsenchyme organs and tissues, Sut
the problen ras to detervine the foras and their scope and we aust
eersp the chanicteristie morphological chances seen in radiation
fata.
Sec.ritsyde
;
This was my first exporience with these complications but I would
diasnose hemtic degoneration followed by cholemla. As we all inow
very well, ths liver is the largest organ which eliminates toxic sub~
I presuza that the radioactive
ater.eca and in the case of ir.
@le-cuts, witch destroy nucled, entcroa his tody throuch the mouth or
skin and thus cau3ed these changes in tha liver. Other causes then
piotuced serious degencration in the livor which was alrwedy danaced,
43 Dr. Kucatordi hes explained in the cas3 of Hr.
there was
hesctorodetic dyafunctica etrrespau:ding to .wiregonsrative ane-La
enustd by the Elind ash, and neturally bleed or plasza transfusion
was required, For this reascn tho disease wis often called sercus
hap:titia, which 4s distinctly a possibility, Hoover since this
matter will ecacern the course of future tharapy in Japan we will
cenaust cuseful atudics and furnish jou with our fintings for further
cynthi3sia. Cur findinza in tha Liver wera very siniler to tha firndinca in sercus hepatitis or infesticus hopititis; but we tmnt
YS 002 ARCHIVES