CONTENTS Surgical Cases... ccc eect cet 31 Gross Appearance...........0c ce cede bese cece sete eeeegeeevteectes tee Genet tittcntterneteee + ee 31 Microscopic Appearance... eects boc cecteecette Seecebteeetteee cette cent ceneees 33 Thyroid Function Tests Related to Thyroid Abnormalities and Growth Retardation........ 33 Results of Thyroid Hormone Therapy...........0...0..0... ceeds rete ctneeieee Goer ceeseceesetetessceteeieneeeetens 40 Discussion of Thyroid Findings....00.000.000.00. 0c cece cece eee eter ect t rect s ctor ctececteeetenseteees 40 Aging Studies... ccc ccc cece cee ceee cent eee eet ee ence te reettetenr civenentttnene ttistsceetcseis eeiseseeeeeenien 43 Methods. 0.0... cece cee cnee cence ener eeecteecerenivetes Gtey Gey ceeetctceeee cay cevteteceeeyeos teeeusesseteerevteeesteees 43 Integument.... eccentric teen oocee beecevey dteveitatectevsnevituestanseesiesttceste ae 43 Special Semses. 2.00... cece cccecceeeeeeceeeeeseeseeee cots cseeeesseeseceteceescrecsreeersceevsegnresseretecsseresomersaees 44 Cardiovascular Changes.......0.000.000 00000 cc cee eer teteecnteeeee: ce euecutetcseeeteseuttens ee cartes: 44 Neurological and Neuromuscular Function. ......00000000 00 ccc ce ceeeeteeee trees teevteeeeens . 44 Miscellaneous Tests.........0..000:::e eee bites ubteetteeeteectteteiees cdc eeeeetetetsetertees ceetuneecees 45 Correlation of Data... eect deed dee cseteeetteeerteeeieteieateveteserenees 45 Results of Aging Studies........0..00..0c cc cccccec cee cere eee conte torte tees eter ecneeeretiesstecvigetevitesreetnennteern 46 Discussion of Aging Studies........0..00.0. cece ccc eect sete tee eeee estes etneteets" eetteeeeebite eeeeeeneees 46 Hematological Studies... coc dee seat cess eecaeeceaeecereecereeesseeneeecteesereeentieeeeneeetens 31 Rongelap Population... ccc ec ccc cece eeere tree ce eee ceesetenesneesetesecsensoeetitesatecieserenenerecrean 31 Ailingnae Population... cece cree cree crete cet tces cere ctcieeeenectetienerntirnity seteviestttnsareresercts 54 Utirik Population...ae cette ebeeccteegeseeceseeeeteeeees Loe se etecctttccctescstevetteaeetesteaeennteees 54 Children of Exposed Parents..........0.0:05.0ccccccceteeeeetteetteete b ceaettcsees Soot lee getteeeteeeeeeieeeeiees 35 Leukemia Survey..............ccccecccccesceececnee cece cee cece ceee sent eccseccseecitenssscescveeseetieeciescieseneseneeetneee aes 35 Statistical Analysis of Rongelap Blood Data... ole cette cee cere ter tetee ren 35 ChromosomeStudies............ see eceeeceeeaseceecseenseecesies cess etesceesecnecceeeceescnteeeeeetineciserseueetrereetnareseees 35 Other Laboratory Studies... ccc ccc cece cece eee eeesescte ces tniesescetsesesstatesestenietecenees 37 Total Blood Volume and Red Cell Volume... 000i te etnies teeter 57 Test for Australia Antigen... ccc ecrene crete eeseeterntes rutevrtienvennstees en ne 38 Estimation of Internal Body Burdens of Radionuclides. ...0000.0000000 000 00 cee. veeette settee a. §=—5B Whole- Body Counting.......00.0 tects cecence bee veeres a. 58 Radiochemical! Analysis of Urine... ccccccceee cee e eect tee ct csesereseieteteetieeaneieettenss 59 Results and Discussion of Body Burden Estimation....0.000000.000 ccc cee ere 61 Comparison of **"Cs Levels in Marshallese and Alaskan Eskimos............... ree 63 Radiochemical Analysis of Coconut Crabs... eee 63 5008282 iv