24 T T 7 7 T T T T =r SKELETAL AGE ASSESSMENTS BOYS 1957-1965 | of _ 225! r T Y T ! SKELETAL AGE ASSESSMENTS 3 GIRLS 1957 -1965 { l s Z = ~ 50. g 150 ° 2 125 - oo 100 - MALES EXPOSED 4———s MALES UNEXPOSED o———o i ° [~ | | f l 25° * 4 4 ! = Gy | ° 2. | | ! L °—~=O75-—i10”—=‘i2SCs(“‘TSKO , | | CIPS | ! ' 20022550 CHRONOLOGICAL AGE {MONTHS} 25 2 ' | FEMALES EXPOSED =—=——4 a L : 1 | -u ool 4 50 ! ; 4 o i 4| ok 6 i 4 | | TO 125 \ ~ ws SKELETAL AGE (MONFHS} ~ 200k | | Fe T | D 7 l 25 FEMALES UNEXPOSED o——o | 1 | 4 im +50 mn 75 | 100 125 1 (50 (75 | 200 225 CHRONOLOGICAL AGE (MONTHS) - Figure 18. Figure 19. THYROID FINDINGS exposed on Rongelap: 150 rads (from direct measurement of urinary **'I),*° 100 rads (byindirect measurements on pigs removed from Rongelap plus Marshallese urinary excretion data),”* and 160 rads (based on recent recalculationsof early data*’ — see Appendix 2). Thelast recalculations were based on analysis of pooled urine samples mainly from adult Rongelap people taken 15 days after the detonation; an estimate of the one-day thyroid content of ?*"I was 11.2 pCi (3.6 to 22.4 uCi), assuming that 0.1% (0.005 to 0.2%) of the maximum thyroid burden (not corrected for physical decay) was excreted in the urine on the 15th During the past 3 years, the development of thyroid abnormalities in a significant numberof the people exposed on Rongelap, and in one from the Ailingnae group, has resulted in extensive thyroid studies and surgical intervention in some cases. The examination andtherapyof thefirst 6 cases of nodules of the thyroid gland have been described.'°-*3-?4 Since then, the number ofcases of nodules and hypothyroidism has increased to 18, and the new cases are described below. The Radiation Dose to the Thyroid Glands The dose to the thyroid gland from radioactive iodine is determined byits uptake by the gland, its half-life in the gland, thesize of the gland, and the relative proportion of the several radioisotopes of iodine involved. Therelative distribution of radio1odinesin fallout depends on the type of explosion but in general is well known. In addition to '""l, the isotopes '**I, '*I, and to a less extent '**I contributed significantly to the thyroid dose. The only direct data available on the Rongelap people are radiochemical analvses of pooled urine samples taken 15 days and longerafter the fallout. Three separate estimates have been made of the dose from radiolodines to the thyroid glands of adults 5008308 | 25 day. The dose of 160 rads to the adult thyroid was calculated from oral intake and inhalation of the various lodine isotopes, considering their fission yield, the average energy deposited in the thyroid gland per disintegration, and the time of absorption. The dose tg the thyroid glands of children <4 years old was then calculated by means of these factors with consideration of pulmonary function and the thyroid size of a child that age.** The main sourceof iodine ingestion was considered to be water, and since it was being rationed at the timeofthe fallout, it was assumed that the children drank the same amount of water as adults and therefore had the same thyroid burden of radioiodines. The small size of the childhood thy- o r |