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purpa, end hypoxia due to enem4a, any one of which may be fatal,
Many detailed -
desertptions of the pathogenesis of these phenomena have been published (1-4, 12-16).
The above picture
of radistion syndromes is based on animal experimentation;
however, human experience particularly as observed at Riroshina and Nagasaki and
in the Marshallese natives has indicated that man probably corresponds quite
closely to the general marmalian response outlined above with the exception of
some differences in time cf occurrence.
The CNS apparently was not observed by
the Japanese at Hiroshima and Nagesaki.
Cne would not expect it to have been
observed since doses to produce this syndrome were well within the area of almost
total destruction.
The GIS with deaths in the first week are well documented
clinically and pathologically as are deaths from the HS.
However in the case of man,
deaths from infection were most prevalent in the second to fourth weeks (maximun
incidence during the third week) and from hemorrhazic phenomena in the third to the
sixth weeks (maximum incidence in the fourth week).
In the Japanese, after the
bembing of Hiroshima and Kegeraki, deaths from radiation injuries were occurring as
lete as the seventh week.
This is in contrast to other animals where deaths from
the acute pkase are uncommon after the 20th day.
PROBABILITY OF SURVIVAL AS RELATED TO SYXPTOHS
Predictions of the effects of various doses of gamma radietion are essential
to military and civil defense planning.
If the absolute sensitivity of man to
rediation were known, and if it were practical to determine the dose to groups
under catastrophe cenditions, a realistic statistical prognosis could be made.
However, these predictions cannot be made accurately at the present time.
Problezs
invcelved with estimation of dose received by the injividual, present real practical
difficulties,
It is probable that dose estimates will be evailable from dosimetry
devices or-from dose contour lines and the position of individuals during exposure.
The difficulties of relying heavily on the dose estinates for a single individual
are apparent. -The exact position of the individual and the degree o@& shielding
DOE ARCHUIVEeS