72 Hematok T. KUMATORI order of 350R to ¢ and LALANNE, C. M., Kivicra, K., Ikepa, N., Krmura, K., Kawanisul, H. and Kimura, M. (1956): ibid. I, 521. logie,6, 561, (1963) Korasta, Y., Kumatori, T. et al. (1955): Iryo, 9, 1. Tonizing Radiation Kumatonl, T. and Miyvosut, K. (1963): Diagnosis and Treatment of Radioactive Poisoning, 253, International Atomic Energy Agency, Vienna. Kcuvatoat, T., Isninara, T., Uepa, T. and Mryosui, K. (1965): Medical Survey of ietic tissue, Int. A (1967)). We have compar the curves of Yu Japanese Exposed to Fallout Radiation in 1954—A Report after 10 Years, cases, and here a¢ National Institute of Radiological Sciences, Chiba. same difference, < tion of these data the difference bet: Mrkamo, Y., Mryosut, K., SHimizu, K., Isutxawa, K., Kurtyama, S., Koyama, Y. and Kusatont, T. (1956): Research in the Effects and Influences of the Nuclear of Hematology, 1, 29, Pan-Pacific Press, Tokyo. Mirosui, K. and Kumatort, T. (1964): Nihon Ketsuekigaku Zensho, 3, 660, Wee ge St Meaty Mivoset, K, and Kumatoat, T. (1955): Acta Haematologica Japonica, 18, 379. Miyosui, K. and Kumatoat, T. (1962): Proceedings of 8th International Congress cases and the p: patients was that patients the dose with a maximum ° minus 4 per cent, of accidents the u less, and of the o = Bomb Test Explosions, II, 1313, Japan Society for the Promotion of Science, Tokyo. Maruzen Co., Tokyo. Dr. KuMATORI: opinion. In my DISCUSSION damaxe, and its relationship to external or internal radiation exposure? Dr. KuMatori (Japan) : Since this fatal case was anemic and revealed bone marruw aplasia, he received blood transfusions. Therefore, serum hepatitis can’t be ignored. However, at the same time the existence of radiation-incduced liver damage should be considered. At present it is difficult to decide the cause of his liver damage. We should consider the probability of the radiation-induced liver damage, because in some publications we can see a similar histological picture of the liver of a patient who wasirradi- ated therapeutically. Dr. Sanc Kumatori, something dencies on (Korea): I thank you I would like to ask about hemorrhagic these cases, Would Dr. you tenyou tell me how long did hemorrhagic tendencies continue after the irradia- tion? Dr. Kumatoai: In my cases the he- morrhagic tendencies were not so ‘severe. The prolongation of the bleeding time was observed in a few cases. You can see normal bleeding time in normally 3 minutes, and in 1 or 2 severe cases the bleeding time at the critical stage was as long as about 10 minutes. I think this came back to normal at about 10 weeks or so after the exposures, though I have no correct data here. Dr. Sanc: And how about the fibrinogen concentration ? Dr. Kumatoni: Fibrinogen concentration was almost normal from the beginning of the examination. Dr. Tupiana (France): I would like to ask Prof. Kumatoni if be has an idea of how uniform was the dose delivered to your fishermen. I ask you this question because we have a rather large experience of total-body irradiation for mostly kidney transplants in human patients, and there are 2 main differences between your results and the one we have also. The first one is that aplasia of the blood occurs much earlier in BOON, aaa? comment on the nature of the liver most cases. In our cases, we used Duke's method. The bleeding time is ia Concerning rats Dr. Citrton (U.S.A.): the one fatality, would you care to our patients, and the rigidity also occurs much earlier. The 2nd one is that the minimum number of leukocytes is much smaller in our cases, being of the order 1 to 200 leukocytes per cubic millimeter, after a dose of the 3 4