ry / Mr. John T. Conway zm ~2- May 12, 1966 The only instance of cancer of the thyroid was scen in a Rongelap woman who was approximately 30 years of age at the time of exposure. The noduler condition seen in the young people is not a cancerous process, although cancers of the thyroid often grow in nodular fashion. In August 1965 nearly all these people were placed on tetraiodothyronine, a synthetic thyroid hermone, on the basis that such therapy would modify the incidence and/or course of the nodular process. It appears to have been partially effective but it is still too scoaqn to be definite. Forty children ofthe same age grouping who were on Utirik Island and received 14 R whole bedy plus proportionately smaller thyroid exposures were also examined. They showed no signs of thyroid nodules or thyroid disease. In addition, 194 unexposed Marshallese now living on these islands were examined; three instances of nodules were found, all among people more than 47 years of age. Five of the Marshallese with nedular thyroids will be brought to the Brookhaven National Laboratory during May 1966 for further diagnostic study and posaible aurgery. One is a 46-year-old woman; the others are girla 13, 13, 13 and 20 years cid now. They will be accompanied by the Rongelap school teacher who will act as interpreter. The treatment and travel of these six Marshaliese have been developed with cooperation of the Honorable Wilfred Goding, High Commissioner, Trust Territory of the Paciiic Islands. You will be kept informed of the progress of these atudies. An advanced copy of the public announcement on this subject prepared by the Brookhaven National Laboratory is enclosed. Sincerely yours, {s/s S. G. English S. G. English Assistant General Manager for Research and Developmeat Enclosure: "Five Marshall Islanders to be Examined at Broskhaven Medical Center,'' announcement by Brockhaven National Laboratory J CAE