.
\
3
eoecen ees GOUNtS Gude
Seer”
op bone ~- res vrepar.tiono.
in the quality of the uresyers
fone, whieh lace
The laproverent
Followed the intre-
duetion of the oresent technique, ia evident from tie finding that
in 1602 eelle fror bone warrov oreperstione only. 85.02% had a count
of 46 chromoaones,
‘$A enomperison of the gount jiistributions in
the pre-ex:osure blood ernplec from the two orcientea cited below
with thea in “ableea 1 and 2, ahows thoae distributions to be within
the normal Prange of values fu. the present teehni-jue,
The two male patiante studied wers given X-ray treatment
for enkylosing spondylitia.
The fireat patient received treatment
te the whole lon:th of hie spine eni to hie sacro-ilizg joints
between 18/7/60 ani 29/7/60, pn total ekin dose of 1500 rade being
given in 10 equal frooctions,
In thn second putiant, the effeot
of a sincle dose of X-rays, 250 rads to the skin over the spinal
column alone given on 10/8/50, was studied over a period of ten
daye by serial vbiood a:ltures,.
The field arrangeaents and the
Xepay physical chrracteriatioa sre uncon for Lath ontiente in
Fige 14 and 18.
Calls wera select -d for counting orovidjed thst all the
small chromesomes (Nos, 13 to 2: ani the Y chromosome in the Denver
Classification) were essily identified, .2n3 in ovary selected oell
these were analysed,
it will be soen from Tables 3 and & that
polyploid cells were noted in most >: the preparations,
These
polyploid oelion are not inoluded in th: chromosome counts as they
ed a dee
ean be reoornised without a pesne eount being mode,
For
purposes of comparison, however, an epproximate neseure of the
frequeney of polyploide is indicated hy th- faot that only two
were noted during the study of the 694 cella listed in Tables 1 and
2e
The lest technienl point to be mantioned ig that ona of the
common effects of radi: ciom was the »oroduetion of chromosone
Pe we
©
DOE ARCHIVES f