C.W. Mays - Page 9 incidence of 425 thyroid cancers per million infants each receiving one rad; (B) a linear dose response, but iodine 131 irradiation only one tenth as effective as X-irradiation; and (C) a high threshold. Assumption (A) probably sets an upper limit,for it is unlikely that iodine 141 is more effective than X-rays. Assumption (C) certainly sets the lower limit -- the number of induced cancers cannot be less than zero! Assumption (B), while between the upper and lower limits, is not necessarily the best estimate but it yields reasonable values for planning the experimental search for thyroid cancer. Estimates of the number of radiation-induced thyroid cancers which night appear during the lifespan of the 250 oan infants for doses of 1.3 - 10 rads are compared in Table 3 to their expected natural incidence by age fifteen. Table 3 ESTIMATED THYROID CANCERS FOR THE 250,000 IRRADIATED UTAH INFANTS ASSUMPTION (A) (B) (C) NUMBER OF CANCERS Iodine 131 effect equals x-ray effect Effect equals 1/10 of X-ray effect High Threshold ii - 88 1 - 9 0 "NATURAL" INCIDENCE BY 15 YEARS OF AGE 6 Similarly, it is instructive to calculate the anticipated number of radiation-induced thyroid cancers which might appear during the lifespans of the 565 infants in Washington County, Utah, exposed to higher thyroid doses (estimated at 120-440 rads”) following the "Harry" shot of 19 May 1953. in Table 4. These estimates are shown DOE ARCHIVES

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