wee stay tm Ladhe / Table 2 indicates that about a quarter of a million Utah infants were exposed to fallout iodine 131, with an indicated average thyroid dose of 1.3 ~ 10 rads.* The significance of these exposures is not the size of the average dose (which is srall) but in the enormous number of irradiated children. THYROID CANCERS The natural occurrence of childhood thyroid cancer is extremely low. Values from Mustacchi and Cutler indicate that by age fifteen years only 25 thyroid cancers are expected to appear per gillion children.® Thus only about six "natural" childhood thyroid cancers are anticipated in the 250.17 Oeosed Utah children by age fifteen. The fraction of these so called "natural" cancers which were in fact induced by medical X-rays may be appreciable. In a series of childhood thyroid cancers collected by Winship and Rosvoil, about 80 per cent showed a history of prior irradiation.” in the United Kingdom only about three children per million develop thiyroic canccr by age fifteen, 1° X-rays can indice thyroid cancer, About 20-30 years ago, it was common in some hosnitals to X-irradiate infants in the neck region for benign conditions. Thyroid cancer has followed °-n an unpleasantly large number of these exposed children. ? Beach and Dolphin? 1 founda reports of 132 post-irradiation thyroid malignancies in the published medical literature; the additional number of unpublished cases remains unknown. They analyzed the relation between incidence and dose in 4673 exposed children for whom the individual doses were obtainable. The incidence of thyroid cancer increased with dose to 1.7 per cent at 500 rads. assuming *Vyearliercrudemethods (see Ref. 5) yielded an estimated thyroid dose averasing 4.4 rads to this population. I am pleased at the agreement. DOE ARCHIVES 43

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