32
with marked growth retardation (Nos. 3 and 5),
T, levels before surgerv were lowerin subjects exposed in childhood than in unexposed controls.
Subjects exposed as adults who developedeither
benign or malignant thyroid lesions did not show
notable impairment of thyroid function. The
serum iodine levels of exposed and unexposed
people for the past 15 years are given in Appendix 8.
In 1965, the rates of urine and thyroid accumulation of 1321 were measured over a 4-hr period in
21 Rongelap subjects, of whom 9 were unexposed
and 12 were exposed as adults.!8 The data are
summarized in Table 26. Compared with North
American normal values obtained in 196518
(urine, Agi #2; thyroid, Ag, 2=1; thyroid fraction
= 0.33), both the exposed and unexposed Mar-
shallese showed slow urine and thyroid transfer
rates of extrathyroid iodide but a high thyroid fraction. Similar studies done in 1972 on ‘2? Rongelapese without detectable thyroid abnurmalities,
Table 28
Thyroid Status of Exposed Rongelap Subjects Without Recognized Thyroid Lesions, 1974
Subject No.
Age
and sex
(1974)
4M
58
6M
7M
9M
21
36
42
10M
44
Plasma Ty, ug/dl
Pre-TSH
6.9
6.8
4.7
4.5
9.2
12F
16M
24F
38
39
33
6.5
6.4
8.2
35 M
37M
33
40
5.9
4.6
64
6.0
SIF
66 F
68 M
70 F
73M
76 M
78F
80 M
S1F
82 M
83 M
85 M
1F
1iM
14 F
22 F
45
52
64
35
38
3t
37
66
28
70
20
20
74
70
45
37
6.9
7.0
8.9
7.9
7.8
3.4
6.3
8.1
3.8
53.8
6.2
78
5.1
6.8
6.7
35
44M
24
5.8
71F
48
4.2
34 F
39 F
41M
65
-
48 F
27M
58 F
63 F
67 F
32 M
47M
Mean + S.D.
35
26
36
79
56
34
24
28
24 hr post-TSH
Increment*
7.8
0.9
8.3
3.3
3.3
12.8
8.7
8.3
12.1
7.1
10.6
8.3
11.5
7.2
12.2
7.8
6.6
9.4
9.1
9.4
10.4
11.8
12.0
7.0
7.1
9.1
7.8
6.7
8.6
11.4
15
0.6
0.8
3.6
2.2
19
3.9
3.5
1.9
2.0
3.2
3.4
5.0
2.2
2.4
1.6
3.9
4.2
1.6
0.8
1.0
2.0
0.9
2.4
3.6
75
ug Ty dl
7.0
3.9
2.1
4.5
<1.0
18.5
9.1
4.4
5,3
4.4
144
3.1
2.6
16.7
21.7
4.4
18.4
6.3
5.1
3.2
39
3.1
6.0
1.5
2.3
4.7
8.8
3.0
3.4
3.8
78
2.3
L.4
3.9
3.0
27
18.6
25.5
212
4.2
5.3
6.3
2.7
10.3
75
8.4
*Normalin 13 Pittsburgh subjects: 4.7 1.0 pe/dl.38
pU/ml
TBG-
binding capacity,
2.7
8.2
8.2
7.4
6.64+1.7
Plasma TSH,**
<1.0
7.0
2.352%1.2
**Measured in pre-TSH samples. Normal is <3 wl ml