Table 26 Kinetic Analysis of 132]~ Accumulation and Excretion in Rongelap Subjects Without Thyroid Abnormality Fraction of extrathvroid I- per day Thyroid fraction, Group — 9 Unexposed adults, 1965 12 Exposed adults, 1965 12 People exposed at age 10-20, 1972 Urine* As Thyroid** N04 Aar/(A21 +61) 0.81 (0.17-1.99) 1.10 (0.34-2.57) 0.79 (0.23-1.47) 0.67 (0.33-1.27) 0.49 (0.26-0.77) 0.38 (0.24-0.65} 1.18 (0.72-1.49) 0.90 (0.57-2.06) 0.43 (0.19-0.58) *X61 is the fraction of iodide outside the thyroid excreted tn the urine per day. **\>, is the fraction of iodide outside the thyroid that enters the thyroid per day. Means andrangesgiven. Table 27 Results of Follow-Up Evaluation of Plasma Thyroxine and TSH in Marshallese With Known Thyroid Lesions (Normal values: T, by RIA, 3.0 to 10.2 we/dl; TSH, <1 to3 w4U/ml; abnormal valuesare given in boldface) 1972 Subject No. and sex Age at exposure Rongelap expused 3M 1 5M 1 Diagnosis Myxedema " 6.7 2.5 TSH, pwpU/mi TSH, pU/mi <25 79 8.9 0 376 1 3.7 6.8 7.4 54M 65 F 2M 1 ! 2 " n " 6.5 149 8.2 <25 1.8 15.3 3 " 23.2 2.0 15.1 3 " 158 19M 21F 3 3 23 M 69 F 72F 15 F 20 M 36 M 61F 75 F iS F 40 M 64 F 4 4 6 7 7 7 8 12 21 29 30 " ' Carcinoma Adenomas ‘ tH " " Carcinoma Adenomas Carcinoma 8F 53 F 51 F 1 8 25 42 F Ailingnae exposed 45 F 32 41M 44 Zn utero exposed 83 M 2ndti Uurik exposed 2208 F 35 2212 F 35 2229 F 20 2221 F 54 " “ 1974 T4, ue/di 33 F 17 F Adenomas T4, we/dl 1973 - >120 - T4, TSH, pg/dl pU/m!l 2.7 3.6 13 1.7 10.1 32 1.7 - 118 - 13.8 TBG-binding capacity, spe T, dl <1,0 20.4 13.4 126 3.4 <2.5 3.6 11.9 32 - 69 12.8 <10 1.1 28 98 <1.0 77 7.0 10.0 12.4 ~ 04 7.2 7.6 881 <2.5 460 9.2 2.7 <2.5 6.4 110 <2.5 172 5.1 6.6 0 11.3 13.9 2.5 4.1 22.7 17.8 7.8 10.6 62 149 59 - 7.8 11.1 <04 98 89 1.3 4.6 23 10.9 7.8 9.0 6.3 11 116 <1.0 <1.0 15 2.8 5.6 <1.0 2.6 1.2 Adenomas Nodule 0.5 cm '73; neg. 74 Adenomas 7.8 7.1 2.0 2.6 12.1 7.4 6.3 - 14.0 94 6.9 <1.0 <0 3.9 Noduleleft lobe 5.6 2.7 4.5 <5.0 6.0 4.4 13.3 Adenomas - - 6.7 - 6.2 7.0 12.9 10.1 2.5 - 3.1 11 ~ 5.1 5.0 5.9 4.9 70 4.4 5.5 3.6 <1.0 9.8 1.4 54 16.3 20.1 35.7 15.6 " Adenomas " Carcinoma(follicular) Adenoma - <2.5 - 10.1 4.6 - 4.9 <5.0 <2.5 <5.0 17.4. 4.6 <1.0 1.7 26.2 17.4 45.5 25.3

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