“a 1034 NUCLEAR SCIENCE ABSTRACTS Vol. 19, No. 6 ated the conversion of MIT to DIT as well as coupling of appeare that some I.C.R.P. recommendations for maximum permissible body burden must be revised. (auth) cation of the #1 concentrated by the oxplant, which was reflected mainiy in its increased incorporation into Ty. However, increased !'1 utilization in thyroid glanda of 17—- 0787 EXPERIMENTAL UPTAKE OF STRONTIUM-85 BY FRESH-WATER ORGANISMS. W.A. Brungs (Robert A. Taft Sanitary Engineering Center, Cincinnati). Health DIT, ard thus formation of thyroid hormones. Addition of TSH to the serum-containing medium {mproved organifi- 17,5-day-old embryonic rate cannot be ascribed to TSH because the serum was prepared from the blood of rats that hed been hypophysectomized 6 monthe previously. (auth) and potassium on the uptake of dissolved strontium-65 by a7se Q1}-UPTAKE IN CERVICAL MUCUS DURING THE MENSTRUAL CYCLE, Hilda EB. Parialer, Alberto B. Houssay, Ana C. Zapeta, Adela C, Valerga, and Jorge F. Cordero Funea (Centro de Endocrinologia, Buenos Airee). Fertility Sterility, 15; 433-9(Aug. 1964). The glands of the uterine cervix concentrate 11 and it appears fn the cervical mucus in high concentrations, Since cervical mucus undergoes cyclic changea during the human menstrual cycle, a compariaon wag made of !?!I uptake by the cervical mucua during the estrogenic and progestational phases of the sexual cycle in normal women, women, The first 320 performed between the I2th ant 14th days of the cycle (firat phase) and the eecond hetween the 25th and 27th days (second phase), by injecting intravenovaly 100 ¢C 'E, Peripheral blood and cervical mucus were obtained at different intervals 20 to 135 min after the injection. The ratio, mg cervical mucua: yl plasma, called the mucus/plaema ratio 1M,P) was calculated for every sample. Curves were obtained by plotting the M,P ratios, the €9-min sample being chosen to represent 1007 valve in each indtvidual curve, The curve representing the first phase of the cycle Increased rapidly during the two hr of the experiment, the 120-min value being 50% greater than the 60-min, The higheet value lu the second-phase curve was obtained after 60 min, it decreased slowly thereafter, Thus "1] uptake was greater in the progestational phase. This difference coincides with the change of other characteriatica of the cervical mucus such ag viscosity, osmotic pressure, transparency, rate of secretion, and chemical composition, To find out If the cervical glands are able to concentrate other ions, these experiments were repeated, using ?Na, 19 three normal women, but Na uptake by the cervical mucus could not be demonstrated. (BBB) S755 ON THE RETENTION OF CESIUM-137 IN PEOPLE. M. A. Van Dilla (Loe Alamoe Scientific Lab , N. Mex.). Health Phys., 11: 21-2Q@an. 1968). Cestum-£37 retention following four cases of accidental contamination was measured ag a function of time in the Los Alamos human spectrometer and counter. Inhalation waa the primary route in at least three of these exposures. A simple exponential function fite the data well, the biologi- cal half time averaging 128 daye. Guth) FATE OF THE IODINE RADIOISOTOPES IN THE Boulenger (CEN, Mol, Belg.). Health Phys., 11: 23-35 Qan, 1965). Fate of the iodine Isotopes and resulting organ exposures were studied using a four-compartment model previously proposed to account for the metabolism of this element. Mathematical equations were established for this model from biclogical data accepted in the human. They were used to calculate the amounts of iodine i231 in the thyroid and in the remaintng bod) as a function of time in case of a single or a chronic contrminatton; in the Intter case three phases were coraliored: rise, equilibrium, and decreaze after removal of the contaminatirg eoutce. The importance of the G ity stable iodine intake fram the food was emphasized. Sse of the theoretical retulte,werg checked by expertrece cgersht , dusters, Caleutstions were exter? Ji> bie the ding dg op TA or to determing the es.° ® ' noe they - - strontium-86 int mie macrochirue. The distribution of ced to a containing macrofeuna indigenous to the Midwest was algo investigated. Of the four cations tested, only calctum wag found to have a elgnificant effect within the experimental range on the uptake of atrontium-66 by smal! bluegille, Date from the pod aptake study indicate that after the 80-day experimental period only 25% of the atrontium-85 remained In the dissolved phase. The total calculated activity in the experimental fauna never exceeded 0.9% of the smount added, The remaining radioactivity was aagociated with the substrate. related to age of the test organiems. (auth) a7Ee ABSORPTION OF STRONTIUM-90 IN MAN. Minoru Fujita Gapan Atomic Energy Research Inst.. Tokyo}. Health Phys., 12: 47-80Qan. 1968). Analyses were performed with reference to the levels of “Sr and stable calcium tn diet and excreta of man. From the data obtained, the abeorption of Sr was estimated. Four healthy volunteers received the same diet for 7 periods, each period consisting of five consecutive days, but, except for the periods examined the subjects consumed any food they liked. The given diet contained nearly 0.56 g of Ca per day. The daily intake of "Sr ranged between 7 and 13 yyuC according to the faliout levels in the diets. The absorjtion coefficient, f,, per §-day period of the four volunteers aver- aged about 0.38 with a large fluctuation of from 0.09 to 0.63. However, values of f; over a considerable Ume around two periods ranged between 6.20 and 0,32, making a strong con- traat with the range between 0.09 and 0.48 obtained for the same §-day period. (P.C.H.) sree FUNDAMENTAL STUDIES ON THE CONTAMINATION OF MILK BY RADIOACTIVE STRONTIUM SPECIALLY, ON THE MECHANISM OF CONTAMINATION, Akira Yuyama, Iwate Daigaku Nogakubu Hokoku, 6: 49-80 (1962), Gn Japanese) The hantem of milk by radi ontium wae investigated by administering “Ca and "Sr to iactating goate. Metabolism changes tn these animals were also ob- served. Experimental methods aad results are discussed. WJ RD.) 8769 CHEMICAL MECHANIOMB UNDERLYING THE BIOLOGICAL MECHANISMS OF THE AGING PROCESS. HUMAN AND ESTIMATION OF THE RADIATION EXPOSURE. J. F. Colard, W.G. Verty. J. A. Henry. and R. R. foc? amail bluegilis, The data also indicate that strostium-85 accumulation is Two ""] studies were made at 2-month intervals in 12 ~—~)8786 Phya., If: 41-6Uan. 1968). Factorial studies were conducted to determine the effects of variable concentrations of calelum, magnesium, sodium, tk me fas n- i Johan Bjorksten and Fred Andrews (Bjorksten Research Foundation, Madison, Wie.}, J, Am. Gertat. Soc., 12- 627~ 3) uly 1964). New data related to the chemical mechanism underlying the blologica]l mechaniam of somatic mutation ag a factor in aging are discussed. It le noted that cell cross -linkage is the initial step in aging and ultimate deatruction of the cell. (J.R.D.) aver PLACENTAL TRANSFER OF F'" IN SHEEP, James W. Bawden, A. Sark Wolkoff, and Charles FE. Flowers, Jr. (Univ. of North Carolina, Chapel Hil), Dental Res., 43: 678-83 Sert.-Ort, 1964). J. A surgical techaique was employed on eight pregnant ewes to gain access to the maternal and fetal circulations with the lamb ie utero. Injections of @F (f mC) were made into the animalg ia order to atady various aspects of maternal-fetal "F exchange, The data revealed that mat 7 al piisma clearance of 'F Le quite rapid and that feral patua levels are relatively low when compared to materocl leva.e, Uptake in fetal dental anc skeletal thames was e ’ oa. Fetal incisor teeth yielded from 800 to 166s rn~ Coord Sere esoniva cot et OR tn