*studied' in humanswithout clearance from FDA, a human use committee, or the

research advisory panelof thestaff.”
- 2/7/73 protocol "for the use of 77Br and 82Br on a labeled compoundin
humans. This is the research which Dr. Kalbhen came to Donnerto do.” From
Dr. Thornton (Tony) Sargent to Dr. James Born.
- A. Dobie Jenkins’ 11/21/78 internal correspondenceto Alpen: "I am wholly
befuddled as to Professor Meyer's purposes and concerns," attached to Meyers’
11/14/78 cover note sent, with Alpen's 8/23/78 letter, to "Committee on

Research on Human Subjects" at UCB.
- "Mortimer": 12/16/77 memo Alpen to Robert Mortimer: "I am not presently doing
researchthat falls under the regulations of the Biohazards Controlpolicy of the
Campus."
~ "NIH Peer Review": 1/76: Budinger, Tobias, Schooley, Alpen, Glaeser.
- "Opalka": Alpen to Ms. Josephine Opalka, Patent Administrator UCB, 7/6/77. "Re:
Specific Sequestering Agents for Actinides... used to remove plutonium from victims
accidentally contaminated." Alpen's professional opinion on patentability. Attached:
Record of Invention and Report of Possible Invention. Compounds developed by
Professor Kenneth N. Raymondand Dr. Frederick L. Weitl.
- "Owens": To Mark Owens, Deputy Division Head, Administrative Division. Form

memo[n.d., probably 1979] to cover compliance with Confidentiality of Medical
Information Act.

- "Schmidt": 12/75 exchange of memos between him and Alpenre: "Research Involving
HumanSubjects." Penciled on Schmidt's memo to Alpen: "Employee Involvement."
Reference to 29?™T¢ [Technecium]-labeled albumin microspheresinjected IV, "calibration

of whole body counters for the detection of lung burdensof 23?Pu in humans."
- "Shanahan": 4/11/79 memo from Alpen -- "following projects are suggested for

candidates for additional funding ...GK0102012 Epidemiology of Magnetic Effects on
HumanBeings, T.F. Budinger"[data evidently obtained from cyclotron workers and
research investigators, according to DOE's 2/13/79 Congressional Budget Request
Narrative for FY1980, in large "ENERGY, Departmentof" folder foundlater in this box].

- "Tobias": 5/16/77 memo from Alpen -- "LBL Human Use Committee has not yet
received the Diagnostic Contract human subject protocols for annual review and renewal
... (If your protocols don't make the June 24 agenda,or aren't approved at that meeting,

we will have to stop all human subject activity on the contract."

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