Table 20 Growth and Thyroid Studies in Subjects With Thyroid Abnormalities - Neck |] Growth Subject No. and sex Thyroid abnormality Skeletal ranking, ye at 4 hr," Statural ranking,” percentile Year tested Chronological age, yr 1965 13 3 <t0 , % of dose Serum iodine, ugh Post TSH Pre TSH T,I PBI 3. M_— Atrophy 9 M_— Atrophy 1965 1966 13 5% <0 17 F Nodular 1965 [5 13%2 90 6.8(°64) 21 F Nodular goiter 1965 1966" 15 15 10-25 9 F Nodular 19654 i6 16 2 M_ Nodular goiter 1965 1966" 13 11¥2 25-50 20 M_ Nodular 1965 19 Adult 25-50 72 =F Nodular 1965 18 17%2 >90 42 F Nodular 1965 15 13%2 10 61 F Nodular 1965 20 Adult 50-75 54 M_ Nodular 1965 13 13 90 19 M_ Nodular 1965 17 15%: 10: 75 goiter goiter goiter goiter goiter goiter goiter goiter 1966 1966" 1966° 1966 1966 1966 1966" >90 36 M_ Nodular 1965 19 18 33° Nodular 1965 13 13%. >90 id F Nodular 1965 goiter 5" 4466 13 10% <10 59°F Solitary 35 64 F Carcinoma 4965 3966" 31 40 M_— Solitary 40 F goiter goiter 1966 1966 £965 nodule “"" 1966 nodule 1965 1.4 0.8 > 120 1.9 3.1 0.8 1.8 149 248 1.8 <0.5 372 8.1('64) 1.3 <0.5 440 125 1.0 3.2 8 7.1 6.5 18 5.7 1.7 (29) (23) 7.9 5.2 4.2 2.6 (31) (3L) 6.5 4.2 a3 - (15) 12(10) 19 " (24)" . (24) . 5.7 4.6 -§7.9 4.9 . 5.0 (24) 17 (9) (14) 7°(20) (38) (19) (28) <17 <3 <17 $3 <17 4.3 <1? 5.9 3.8 197 8.2 5.3 «8.6 4.9 3.4 2.0 3.9 ¥£ * 4.2 _ 9.6 26.6 430 4.1 (16) 159 - 8.3 ~ Serum TSH, ng.’ml 7.0 4.9 3 21 19 8.6 10.3°° 7.3 6.6 23.5 4.8 , - “Nalues in parentheses obtained at BNL. "Relauve statural growth expressed as percenule ranking compared with growth curves of unexposed Marshallese children. Assays in 19635 could not detect levels below 3 nanograms/ml. Seven unexposed children in the same age group had <3 ng mi. Assays in 1966 could not detect levels below 17 ng/mi. Three exposed children without thyroid disease Nos 6,8. and 32) had < 17 ag’ml. Two children exposed i utero ‘Nos. 84 and 86) and two unexposed children hac 1) ng mi. The 1966 levels were obtained about 3 wecks after cessation of thyroxine therapy. the 1965 levels. before therapy was instituted. We are grateful to Dr. William Odell at the Naconal Institutes of Health for carrving out these abSSANS. “Post partial thyroidectomy “While taking thyroxine.