30
°
rn
a
2.70
T
100
© EXPOSED
® UNEXPOSED
& COMBINED WITH STANODARO
ERROR MEANS
180.4447 &*
y® 12,24 + 0.671 «
tok
20}- 3
TT
@ UNEXPOSED
o EXPOSED
180,390: * *
90--
]
6 COMBINED
TT
T7379
e
|
y* 23.830 + 0.9234 x
80}-
Te
2.31
50
233
40
|
l2
TO
l
30
pot
40
50
60
AGE
l
80
70
T
90
t
13
30
PERCENT AGING
T
T
|
° EXPOSED
®
UNEXPOSED
°
COMBINED WITH STANDARD
ERROR MEANS
7
r= 0.99 %*
y* 0.51#0.381 +0.0t 0?
=
.
60
4
50
=
a
40
|
30h
* COEFFICIENT FIR AGE
CORRELATION uF EACH
CRITERION USEG TO WEIGHT
SCORES BEFORE SUMMING
I
* *® CORRELATION WITH AGE
SIGNIFICANT AT 1% LEVEL
j
30
}
40
!
50
60
AGE
70
# ® CORRELATION WITH AGE
|
BO
Figure 48. Biological age scores.
3
|
SIGNIFICANT AT 1% LEVEL
Po
30
40
50
60
AGE
70
80
930
Figure 47. Cholesterol (1957).
]
1
COMBINED WEIGHTED DATA *
80 FTOL
T
|
ioe
2
Figure 46. Potassium, males (1961 and 1965).
100
~“ 160
20
90 * * CORRELATION WITH AGE
SIGNIFICANT AT 1% LEVEL
20
10,
1.52
80 }~
00
|
30-—
4
mg PERCENT
60
PERCENT
ri
g/kg BODY WEIGHT
PERCENT
70
}
90
_
at an earlier time than it would ordinarily be
manifest. One aspect of this phenomenon maybe
related to rapidity ofcell proliferation (generation
cycle) in a particular tissue, i.e., with more rapidly
proliferating cells of the bone marrow, leukemia
occurs relatively soon after irradiation, while
malignantlesions of the skin would not become
manifest until later in this more slowly proliferating tissue. In the Marshallese the high incidence
of adenomatoid goiter in the morerapidly pro-
liferating thyroid glandsof the children may pos-
sibly represent premature appearance oflesions
which are knownto occurlaterin life and thus in
a sense represent an aging process. On the other
hand, the fact that no tumors (except benign nevi)
have been noted in the heavily irradiated skin of
these people might indicate a longer induction
period dueto slowercell * urnover of the skin.
In considering futur< aging studies in the
Marshallese it is hoped t iat more sensitive tests
of vigor and organ function suitable to the conditions of study may be used. However, it must be
borne in mind that such subtle aging effects may
not become detectable by ordinary clinical means