UL LIC NaAllVUildt ACHAeEMY OT sclence’s Effects of Ionizing Radiation for the purpose. LOommittee (BEIR III Report) on the b1010g1Cal has been selected Selection of any of the earlier documents would make rather little difference in the magnitude of the genetic effects estimates. From Table IV-2 of the 1979 BEIR III Report, we get an estimate of from 5-75 genetic effects in the first generation per rem per million live births. This range may be appropriately scaled for dose or for population size by simple proportionality. Specific Genetic Risk Estimates The population dose estimates described allow calculation of an average 30 year population dose for the entire population of the atoll. The 180 people assumed to go back to Enjebi constitute about 40% of the total weighting the Enjebi/Northern Islands and the Southern Islands/Northern Islands dose estimates accordingly, we get ((5.6x0.4)+(0.23x0.6))=2.38 average individual dose integrated over 30 years, or 79 mrem per year (notably, well below the FRC guide for the general population average). The dose proportional adjustment factor is then 2.38/,, and the range of risk from BEIR III is (2.38x5) to (2.38x7S5), or 11.9 to 178.5 per million live births. AS a minimum estimate, we assumed the present population might just replace itself in 30 years; i.e., 453 births. The risk, then, would be (11.9 to 178.5)x453/1,000,000 = 0.0054 to 0.081 additional cases. Assuming a 10.7% spontaneous risk, we would expect 48.5 cases to occur naturally during the same period. Thus the upper bound risk in this case is that the normally expected 48.50 cases arising during the next 30 years might conceivably increase to as much as 48.56, an increment of less than two tenths of one percent. ‘ Assumption of the higher number of 1000 births in the next 30 years simply increases the absolute numbers proportionately: The risk becomes (11.9 to 178.5)x1,000/1,000,000 = 0.012 to 0.18 additional cases in 30 years, against a spontaneous total of 107 cases. To provide an upper limit to credible risk of genetic ill health we might consider a child born to a couple born on Enjebi eight years after the return, they would receive as much as 4.9 rem in 30 years, and the risk to a child born to them at age 30 would be a

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