GC» Congenital anomalies. The incidence of congenital anomalies is believed to be higher than found in Americans. The increase may be due to the fact that these people have been tiving in a relatively isolated area for some 2000 years with prevalent consanguinous matings. d. Laboratory findings of interest. EBosinophilia is prevalent. As pointed out about half of the people have greater than 5% eosinophiles in their differential counts. An intestinal parasite survey at the 4 year study revealed stools positive for various parasites in about 80 to 85% of the people. However, hookworm was the only parasite noted which is generally associated with eosinophilis, but the incidence was too low (about 2% of the people} to account for the gener- | ally high eosinephile counts, responsible. Another possibility is that the incidence of trichinosis ine festation may be high. the island.) The prevalence of skin diseases may be partly | (Pigs are used for meat and rats are numerous on This will be a subject of further study. The low incidence of bookworm would not account for the low hematocrit readings. In fact, there was no correlation in individvuais between hematocrit, parasite infes= tation or eosinophilia. ' ‘i The tendency toward low hematocrits may be related to nutritional deficiency of iron or proteins but there is no good evidence that these factors are involved. These people generally show hich total serum protein levels (mean of 8 g) with increased gamma globulin (mean of 2.4 g). The explanation for these findings is not immediately apparent. An unexpected finding is a generally hich protein bound iodine value (mean value for the population of 9.4 wg/100 mi.) The explanation for this is not apparent, particularly in view of the fact that the people do not clinically appear to be hyperthyroid. Serum cholesterols and creati« nine levels were found to be within normal limits. elle +