1
in Section IV. The other physical findings, which

Table 15

have been carefully tabulated in the individual reports tor each survey, indicate no definite pattern

Composition of Pediatric Groups, 1972

Age at exposure, yr
Rongelap group

-

<10
10-19

In utero
Ailingnae group

No. males

No. females

10
5

9
9

2

+

22
11

19
7

3

<10

Unexposed group
Born 1945-1954
Born 1935-1944

1

skeletal development (left hand and wrist) was

initiated,+! and systematic documentation of anthropometric data was started. The documentation was continued during the succeeding examinations on subjects considered to be in the growth
phase (generally through age 20). The data recorded regularly included standing height (stature), body weight, head circumference, head
width, head length, chest circumference, biacromial width, and calf circumference, and spo-

radically includedsitting height, chest width, chest

depth, and buttocks circumference. (See Appendix 7.)

.

The development of secondary sex characteristics was qualitatively assessed according to the
standard criteria generally accepted in growth
studies (Greulich et al.,*? Shuttleworth*$). Such

procedures included the staging of breast development in girls: estimation of the type, pattern,

and amount of body hair (facial, pubic, axillary,

etc.}. and staging of the growth of penis andtestes
in boys. During several examinations, photographic documentation was doneas partof the
assessment of growth status and physique.
The roentgenographic evaluation of skeletal
development was donebythe inspectional technique of Greulich and Pyle,41 and the American
standards were used for comparison.
2. Physical Findings

The early post-exposure examinations indicated
that the vounger children, in general, manifested
more extensive and moresevere radiation injury
than the older children and adults. Following re-

covervfrom the acute effects of radiation, the over-

all physical status of the children appearedto be
normal except for the subsequent developmentof
thyroid abnormalities, which are discussed below

of abnormalities that would differentiate the exposed children from the unexposed comparison
children. The usual spectrum of infectious and
noninfectious diseases, congenital anomalies, and
phvsiological variations has been noted in both exposed and unexposedchildren.
3. Growth Status

Interpretation of the anthropometric data and
assessment of the growth status of the exposed
Rongelap children have been complicated by (a)
radiation injury to the thyroid gland, (b) partial
or total thvroidectomies in the children who de-

veloped thyroid neoplasia, and (c) the administration of thyroid hormoneto the entire exposed Rongelap population since September 1965. If the

data on the three children (Nos. 3, 5, and 63) who
were obviously hypothvroid and had markedly

small body measurements are excluded, comparisons of meanstature andskeletal age indicated no
statistically significant difference between the exposed and unexposed children for either boys or
girls.
Compared with American norms, the mean
skeletal ages at given chronological ages for each
group were, for unexposedgirls, quite similar, but
for unexposed boys, they appeared to be delaved
by 6 to 7 monthsat each chronological age.
Earlier preliminary comparisons had suggested
that boys exposed at age <(5 years were retarded
in staturalgrowth compared with unexposed boys.
The current analysis excludes those with a specific
diagnosis of hypothyroidism. The individual growth
and developmentcurves for 13 children exposed

at age <5 andtheir controls are shown in Figures

21 and 22. The effect of thyroid treatment on the

two boys (Nos. 3 and 5) is evident. Several other
children (Nos. 2, 19, 65, 42) had a tendency to-

ward retarded development, which may have been
improved by thyroid medication.
Onthe 4 children exposed in utero, careful examinations have resulted in no unusualphysicalfindings. The growth progress of 3 of them has been
similar to that of age peers (see Table 16). One
boy (No. 85) has had a head circumference

smaller than the average for unexposed males and
a slightly retarded pattern of skeletal maturation,
but his statural growth curve was comparable with
that of unexposed males.

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