29 The depressed thyroidal iodine uptake rate and renal excretion rate are puzzling, and no explanation for them is available at thisme. cases have hypothyroidism with no nodules. All occurred in the more heavily exposed Rongelap Development of Thyroid Abnormalities noted in 1963 in a 12-year-old girl in the exposed group, and in 1964 two additional cases with nodules were found in exposed girls 13 and 14 years of age.'°?? In March 1965 three additional cases in exposed people were noted in boys During the past 3 years, beginning at 9 years after exposure, a total of 18 cases of abnormalities of the thyroid gland have been detected. Nodules of the thyroid gland were found in 16 cases, and 2 people except for one womanin theless exposed (Ailingnae) group. A thyroid nodule was first Table 17 Thyroid Abnormalities in Exposed Rongelap People, 1966 Subject No. and sex 3M Present age, yr Ageat exposure, yr 13 1 Year Findings Age, yr 1965-12 Hypothyroid, PBI <2 hge% March 1965; retardation of growth preceded these findings by a numberof years. 3/66 growth spurt and improved appearance on thyroxine. 5 M 13 1 1965 12 Hypothyroid, PBI <2 ue% March 1965; retardation of growth preceded these findings by a numberof years. 3/66 growth spurt and improved appearance on thyroxine. 17 F 21 *F 15 15 3 3 196312 196413 Adenomatousgoiter; total thyroidectomy, 1964. No recurrence 69 F 2M 16 (13 4 1 1964-14 1965 12 Adenomatousgoiter, partial thyroidectomy, 1964. No recurrence vi ue 1 a 20 Mz 19. FED1965 64-8 420030 of 18 5. 41 7 Bee Adenomatous goiter; total thyroidectomy, parathyroidectomvy, 1964. No recurrence. Adenomatousgoiter, partialtthyroidectomy, 1965. No recurrence <= : . Adenomatous goiter,partialshyroidecsomy, 1965. Norecurrence. Mixed papillary andfollicular carcinoma, total thyrdidettemy . urgical and therapeutic radioiodine, 1965; Newmiiiy 1965 “> T¥*~ 1965 14 Three-mm nodule left lobe. 9/66 nodude‘hot ZEwo- mm nodule right lower labe. 3/66 ho ales Zttargeyneat 1% X normal) entire gland; firm 5-mm nodule¥ight tobe. _ 4/66 subtotal thyroidectomy: adenomatous goiter. : > * § 1965 19 : ae wnat to 8-mmamooth nodule left lower pole. 3/66 1-cm nod bbe. 7/64subtotal thyroidectomy: adenomatousgoiter. - ¢ 1965 We Two-mm nodule right lower poie. 3/66 no nodules detected. 1965 45 Five-mm nodule midline. 3/66 same. 7/66 subtotal thyreldee tomy: adenomatousgoiter, “ze 54M 13 l 1966 13 Nodular enlargement {(~142 x normal) left lobe and isthmus with 2-mm firm nodule. 19 M 17 5 1966 117 Multinodular soft enlargement entire gland (~1'2 x normal). !cm nodule right lower pole. 36 M 19 7 1966 19 Slight nodular enlargement, entire gland. l-cm nodule, not clearly demarcated, at right lower pole. Manytiny nodules over surface of gland. 33. 13 1 1966 13 9/65 questionable irregular gland. 3/66 definid-mm nodule F left lobe. 7/66 subtotal thyroidectomy: adenomatousgoiter, Hurthle cell adenoma. 65 F 13 1 1966 13 9/65 questionable smail nodule. 3/66 5-mm nodule right lobe. 7/66 right subtotal thyroidectomy: adenomatous goiter. *Exposed to only 69 rads whole-body radiation and presumably proportionately less thyroid dose.