Si dmatatieteee ketal 2 2. woman in the control group who had developed a thyroid nodule. All of these cases are being brought to Brookhaven for more complete thyroid studies followed possibly by surgery in Cleveland by Dr. B. Dobyns. There were two other exposed Rongélap people with borderline thyroid lesions and they will be observed carefully on thyroid treatment. Thyroid Reserve Study. Drs. Jan Wolff and Kund Knudsen were in charge of this study. In view of uncertainty of complete compliance with the thyroid treatment program in some people a test of thyroid reserve was done in 41 people in this group who had not developed thyroid abnormalities. Thyroid hormone treatment was discontinued for 2 months prior to our examinations and then plasma samples were taken before and after the injection of 10 units of TSH for later analysis of hormone levels. Plasma samples for hormone levels were also taken on other people. In order to test environmental iodine levels on Rongelap diet and urinary samples were taken for iodine analysis, Diabetic Study. Dr. Reed Larson, headed this survey. This disease which is known to be of high incidence along with cataracts of the eyes in the Marshalls, and this survey was carried out in Rongelap and Utirik people to determine its prevalence and attempt to advise the Trust Territory medical people concerning this serious medical problem. The volunteer response for this study was most gratifying - a total of 360 people being tested. Diabetic questionnaires and pre and post prandial blood sugars are being analyzed. Judging by the number of positive urine sugars, there appears to be a high prevalence of the disease mainly.in those greater than 40 years of age. Infections and need for amputations are a source of great concern to the Marshallese medical personnel. Genetic Studies. Studies for possible inherited defects in children of people of exposed parents was under my supervision, and is being carried out in collaboration with Dr. James Neel and Dr. Arthur Bloom of the University of Michigan. During this survey blood samples were collected for a variety of tests for metabolic defects and bucal smears for sex chromatin studies on 71 children of exposed parents, 24 exposed parents, 58 children of unexposed parents and 37 unexposed parents were examined in this study. tion was carried out on each child. A brief physical examina- No obvious congenital defects were noted. In view of the general negative nature of the studies of the first generation Japanese children of exposed parents it seems unlikely that positive results will be seen in this group. However, the psychological benefit associated with negative findings would be reassuring to the people. Radiological Surveys. Radiological surveys were carried out at Utirik, Rongelap and Bikini Islands. At Bikini there were about 80 people living there, 30 of whom (3 families) of Bikinians who have moved back, and the remainder are workmen and their families. In view of the anticipated return of larger number of Bikini people to their home island in the near future additional data collected on this island will be given prompt attention. Whole-body gamma spectrographic analyses were carried out by Dr. Cohn and Mr. Rothman and environmental sampling by Messrs. Greenhouse and Ash and Dr. DOE ARCHIVES