Study of onaterogmete: Injury Responsible Agency: National Military Establishment ; ; Objective: Toperform certain routine homatoligic examinations NMRI, For comparison with results obtained at Bikini ond in the y tendenc gic hemorrha the of course the and nature To study the in irradiated animals. Proecdurc: Routine, complete studies of the homogram will be Wodeinthe surviving large wnimals, The studies of the hemor- rhagic state will be confined to histologic examination of appropriate tissucs, and to biochemicnl studics of plasma, quick frozen at otc, Project 7: -55°F, and returned to NMRI for fractionation, Study of Particulate Fission Products Responsible Agency: University of Rochester Objsotive: To study the distribution in lungs ond other fissues of radionctive fission products, of dust containing induced radionetivitys; using animals exposed at various sites, Procedure: .is amended, selected tissues from animals exposcd in 3e2elel would be aviilable for preservation for radio~ autography, microincincration, and other suitable studies. (See original proposals 34262023 Se2e2ed3 3.20204; 5a 20,0 and 3.2,2.4.1) Rospyunsible Agency: National Military Establishment Objectives To study the distribution in animals cof fission products inhaled and ingested in oreas of fall-out, Prosedurer Where fall-out is expected shielded laboratory ‘Srnimalswould be expes:d for varying intervals of time; and in known arcas of firll-out laboratory animals end indigenous forms would be collectud after cxpeusure and studicd for the distribution and varicty of fission products in the lungs ond bodys UCnl* Responsible agency: Crocker Laboratory, University of California Objective: To investigate th> behavior of radicactive aerosols produced by nuclear detonation, using expcrimentsl animals (rats): to evaluste and estimate the possible hazards to humans inhnling radionctive dusts and mists, Procedure: Animals would be placed down-wind, suitably shiclded from bemb radictions, If possible others would be placed in drone aircraft, S,udies of chemical species cf radioactive aerosols, their distribution, cte., would be performed using alpha, beta and gamma counters; Project 8: cleckroscopcs, ctce Biological Dosimetry Ovjcctives: This scrics cf proposels involves the use of certain biological agents as dosimeters, on the basis of extensive laborstory stulics, Procodure: The dosimeter material would be placed in suitable containers, and in allthe animal exposure containers. It would alse be placed behind experimental shields, and in the high dose range. It is planned that the dose renge: 20-600r would be monitored by Tradcscantia; 50-600r by the CF-1 mice; 500-5000r by Neurospora; 5000-20,000r by Aspergillus; and 5000-50,000r by Zea, Responsible Arencics: Tradescantia Oak Ridge Naticnal Laboratory, and NME Zea U.S.Department of Agriculture, and NME Aspergillus Onk Ridge Nationel Laboratory, and NME Responsible agency: Objective: * Submitted Los Alamos Scientific Laboratory To use alterations .f the size of Splecn, thyms, and changes in the ratio: white pulp/red pulp after 250 KV x-ray as an indicator of equivalent rediation. It is proposed to attempt biological monitoring of atom bomb redistion in certain localities by taking advantage of this effoct, Procedure: Mice whose response to 250 KV x-ray is well known would be exposed in the approximately 50-600r range in locations where integrated dose measurements are desired, as behind hiclds, in drones, etc, Aporoximately 5 days after exposure the animals will be sacrificed and the measurements made, too late for action by Committce C-3 am wo tte Project 6: 2 TT COUT TET TSR ty 1