c enzyme systoms is
Knowledge of pattern of chango of tissu
;

sought.

;

be quick
Procedure: Tissues obtained os in Belesee Will

Fronsn at

4-5S°C and transported in this state to the Army

Medical Conter for enzyme system studics.

NCT**

—
Responsible jgoncy: Notional Cancer Institute
ion
radiat
bomb
atom
the
of
s
effect
the
Objectiver To study
a source of
on the hematopoictic system, on longevity, as
mice.
genetic effoct, and as a carcinogenic agent for
ces
Procedure: Animals would be exposed ss in 3.2.1.1 sat distan
ups
Ghore sublethal doses could be expected, Long term following
and breeding studies would then bo conducted after return
the animals to the National Cancer Institute.
Project 3:

Bele Sel

Responsible
Objoctive:
area burned
Procedure:
to separate

Study of Thermal Injury

Agency: National Military Establishment
To study the relation of the mortality to surface
and to the degree of the burn.
An attempt will be made by suitably timed shiclds
the majority of the thermal exposure from the

ionizing radiation exposure.

‘Suitably shiclded pigs will be

placed where burns of varying severity can be anticipated,
The influonce of the burn on mortality, end as a complication
of radiation injury will be studicd,.
Zeladed

Sele bed

Responsible 4eeney: University of Rochester
Objective: To comparc atom bomb flash burn with matcrial from
Bikini, and with flash burns produced in the laboratory.
Procedure: Suitably shiclded pigs will be placed where burns
of varying severity can be anticipated, The histological
character of the burns, and related phenomena will be stucied
in an attempt to evrlunte other atom bomb flash burns, and
laboratory flash burns,
Responsible Apency: Argonne National Laboratory
Objective: To analyze histologic changes in tho skin of pigs
exposed to thermal radiation, for comparison with the findings
in the skin of the victims of the Los 4lmos accident.
Procedure: Young pigs would be exposed, suitably shielded
from blast, and by timing devices from some of the ionizing
radiation,

Specimens of skin would be removed,fixed and

returned to the U. 8. for study.
Project 4:

Seleded

Study of Blust Injury

Responsible Agency:

Objective:

Netional Military Establishment

‘fostudy blast injury using improved containers

basedonexpericnce at Inyokern and Bikini,’ There were serious

discrepancies at Bikini between the degrce of injury and the
estimated overpressurc, with lethal effects from peak pressures
that are not lethal with H.E. Further study of this is desired,
Procedure: Small animals, shielded from thermal radiation
would be cxposed in various positions related to blast measuring devices, They would be sacrificed as soon as recovered
for study of blast effects,
Project 5:
Buael

{Part M-5)

Study of Simulated BW A,-ents

Responsible Agency: National Military Establishment
Objective: To study the effect of atom bomb radiation on the

Simulated BW agents currently under study by the Chemical Corps,

Proeedurc: Simulated agents, protocted from thermal radiation
would be cxposed at various stations where predetcrmined radintion intonsity is anticipated, Bacteriologic studies of the
growth characteristics of these agents would be conducted at
Eniwetok and in the U.S,

** Proposal submitted too
inte for action by Committec

C- 2

AD AUITITC

3.20464
cont'd

RN

-

woah

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