XM

treated ceses yiela carcinoma; nevertheless, the data suggest that 200 r
is a potentially carcinogenic dose to the infart thyroid.

While the possi-

bility exists that the carcinogenic action may be an indirect, hormonal one,

“4t must still be recognized that this, like leukemia, is an instance of
Bignificant carcinogenesis by less than 1000 rep.

It seems likely that the

infant thyroid is unduly susceptible, but that the adult thyroid is not.---"28
Table Two irdicates the amount of ingested fission product activity
to produce one rad dose to the lower large intestine and Greph Five shows
tke relative doses to the gastrointestinal tract and the thyroid.

It my

be seen that ingestion of a given activity on the fourth and fifth days

may result in nearly two and one-half times the dose to the thyroid as
to the lower large intestine.

For a continuous consumption of fallout

material from the first hour to the 30th day the ratio of doses is about

1.7

36

Bones

It is recognized that the intake and deposition of strontium-89
and 90 are intimately associated with the calcium in the diet.

Whereas

it has been assumed here that a fixed percentage of the strontium intake

is deposited in the bones (Reference Five).

It is realized that this

rethod involves uccertainties, as would the necessary asstuptions to
generalize for a wide variety of calcium--strontium ratios and intakes

DOE ARCHIVES

(2

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