CES
that the major contributory factor to such effects such as nausea and vomiting
associated with whole-body exposures of 100-200 roentgens, may be the result
of the gastrointestinal reaction. Possibly a few hundred rads to the lower
large intestine together with the concom{tant lesser exposures to the upper
large intestine, the small intestine and the stomach (according to Graph Five)
_may be in the range -_whare.. --... radiation sickness might occur.
2. Thyroid
The study and treatment of disorders of the thyroid giand with
radioiodine bas led to considerable information on doses and their effects
to this organ.
(Only a partial list of references is noted; )@9s 23, 2h, 25
a
Whereas these treatments have been principally with ebnormal thyroids, much
of the information may be extrapolated to normal thyroids for the purposes
of this discussion.
In addition there are other data based on normal
thyroids in patients suffering such ailments aa congestive heart gatture ©
The picture that is clearly presented is that of the relative
insensitivenese of the adult human thyroid to radiation.
For example,
Freedberg, Kurland, and Herman, => report, "---Seven days after administra-
tion of 17 and 20 millicuries of 13+, which delivered 14,500 and 32,000
rep, respectively, to the thyroid gland, no histologic changes were notsd
vhich could be attributed to 1/31. --- Fourteen and twenty-four days,
respectively, after administration of 59 and 26 millicuries of I}31, morkea
central destruction of the thyroid gland was noted.---"
Since the first
two patients expired seven days after administration of the D2 tron puimomery edema, it does not eliminate the possibility that the destructive |
un
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