eat i aeedea Ty ee at “ts ‘ aan Pl See aE aeote cmana ote: we car Wid dab ere sadder ite At he . eo : woe webb te nee a he ae ta oak Seopa s at bp ate, Pte a fake Orbea 5 abe Selaate NE aue!obey hose ge aie osteosarcoma. be wainria.lreoma, and fibrasureamc in bone as well as enidenmota carcinamia onthe orsi und rascal cavinigs, ivenphosarcema, myeloid ao opdorenicusa ce a! CaP TARE MES SOIT. beagatoneicel fata tes tthe Utah ouperimants, fugestod Sr has buca esutlaied Woaili wuRSMOBENS tiecrs Ga bone marrow acd the ivmphereticu ar svete? Of noouuture swine as Cescrébed by Clarke et al (sp while Pool et abciaty renert a pen tnerdence cf nore sarcoma in beagles rors Ing quile larie radiation doses how "Sr received hyJAwestion. MoCleflan & Jones (FOR) have ceemmanze? cogently cuch of the information O+ tumor incidence with sadiestrosmatanii andrdals. “though sinall chances in lew pacture have occurred in the 1a. tin, ther Table 1U ts such a usefu: Summary Nei ditis vepreducee oclow(Tobi t. “ur experience with lahaled screctum (109) shows also a predaminence of vuvuars Of pone sinier te the Gian acd Argonne National Laboratorysiudies wih dogs receiving, single intra -encus injections. This indicates that the inhaled suiicrugm compounds are re-oivess roore mobile than some of the insoluble o ides such as Putd, and that bone .. apt to be the chief tissue at risk with v 7a. t a3Jaot va: yy he Hd oY qe ey nh she ste gab dee. ihe . Pete t asates wo wate tat mgs patsyae ow 4 strentium, regardless of route o1 entry, as long as the doses are small. Jl of these studies showsvrancdun to be considerablyless effective as a car“aggen in Bone than radincn and the other alpha erritters. Its effectiveness igative tO Tadnoie sa eae Ccande capecument at Utah is about 0.07-6.24, and woilar effeciuve iiss cuteas canine calc icted from the other experiments. In dogs inating ?'SrCi., cakwieted cumuluive doses associated with neoplasms rangeu ‘rom 4UUL rads to as hign as 22,000 rads (110) compared to much ihackr sioses aAssomated wiir snot. cegcees af development of bone sarcoma . : Gon WEED Pu0dy), Pron, apa ove a.ote emuiers. The new eaperiments coni . CP TN pp dey aD Pe wt ree isis by bets sad beta wamma evaters thon a onint ' ube et oii. apeiesxcipt fer the worldwide popula“Ob USPUSCG tO Maheoba, ob be Grollst sit separ.i2).-, there is only one discrete rapitation oF human aysiibts for esidemiolecies! study which has had exposie Wo radiostrontuit. For a short period lurainous dial painters in Czecneslovakia and Switzerliid used a compound containing °°Sr and 77°Ra. Volf (107) reports on a ercun of 103 cases. Maller anc. ccntrituters G11] veport on 3Oup Cr G2 case, fasafid SasoID, iA tines. gra up, Vile ciiuiivedise abnoraegties wert se obt ueuble Gee conuel rate ans posidve cunical findings J OPCAred, HO TOP ws a owcurred mat coud te aiteicuced 19 the radionucilds OY SOFETE Bone ey co e Wewcesir. ras “er compen There were only 4 case. Pye yoo, ase iCerter tho on SEAM TEMPTING AE body curden for Mapes ~ 7 6o5rs e . ous . . or ae, INE cesar + - op ah kerbehe changes See if) @ ery exposed ia bad BAS. pas vt me owt ae seer ree te eg fel or a s 1 é ou * ap pia we et ee a “sy cd ¥ : webs “ oe a . : phe ir? Wei et bet tae i goal. 6 ba ‘ a . tey want re sotye ad ' : LR me ne the deg cay ah epg ey So H Oey ae eel Fog Mm * tbs pos Posh bw ee ate ‘ mek Gk : ‘ Sek: fies tar wee r so ' top ae J no ee eee & p98 aery individ pe eo. ae Len of thetr study is deveted te alysis of thi: feature ang te phos ue ckinene stalties, They do rerert 6 cases of carcinoma with incideuce in 2°. un: vata! group so low that the probability of secing these boas ; + ~ ‘ Pcmttpe s Me Eres aed fy fea By pk tee be GE at feet CECa Bae ean ola tg ae pe gd " Act Yay ! wey seage nhy “ . . ey yg. ars eet 3 we Sar OMe : ‘ mo ae 4 oF CE Hoe MMR - te tk rye ¢, Ane oar + s oa, see . Fiat Ne . . My 7: . + he. . . Ppt mw le rr + oy : dept Bla Mote ce . ot . ’ 4 eee nt doa Mt, 4 ones, Dee Me asad et bed Ragen ede dat gale oye a te ' Pe . Set te ' fel te: Ee Ree fog ™~ ate ayptediy ‘7 'f og 4 : ‘age:oehatesiw5,EER eR pe aitae Ea Bs ee Yr . ‘ . bbe