EBp.uwemioloric and Field Studies 1966 2 + + Estimate Revised vv Pos. Amouns 4 $192,006 “ L907 a4 astvimate Revised “Neat? - Pos id increase vw Arount Pos. $992,000 +14 Amount +$800 , 000 madiationad Shyroic Initury Ponulation Studies in Uveh, Nevada, Cajectives: und Sclect Commarison States o define the cheracteristics ofon morbidity of thyroid cisease ana mortality of leuxemia in the oooulstions Utan ana Nevada in an e ere to Getermine if the patterns ere Givverent in sections of the States presumed + na ve high concentrai ions of fission product radionuclides from weapons testing Ta lliout versus sec vi aav ing LOW or no fallout from testing. To_Gerens ayroid cisease an wae whe incidence of leukemia in ounties to use as "base lines" Tor interpretation wevada. Tne leukemia mortality data from 19L8-1963 for Utah-Nevada are being analyzed. Pathology reports and persinent case histories for all patients undergoing wtnyrcoia surgery in the two States for the same period are also uncer énlysis. Similarly, whe results of the thyroid examinations conducted on school enileren in Wasniagton eaeoe and Grcham County, Arizona, will be tabulated arter additional clinical follow-uo is completed. Plans are underway to obtain similar data in Utah on owtner age groups, sovulations of otner counties in the same ceclogical Location wiva similar climatic ana demograpnie cnaracteristise and in grouos naving diflerent etanic and socio-economic bacxgrouncs iiving in different geograonical locations. Zt is prooosed that at least six additional school popuievions with aoproximately 2,000 students each be studied in Utah anc Arizona enc four-six comparable groups in other States. Other states being tenvatively considered are West Virginia, Cregon, Nebraska and Colorado. Study of Morolicity and Mortality or Ghyroia Disease Cbhiectives: To estaolish distribution yatterns of diagnosis oF thyroid cisease oy age, 3eK, type OF Glsease, Locale, and year; To estimate tne distribution pavters or the onset of first symptoms oF tayroid Giseasé cy age, sex, and type Of Ciscasea; To esvablish whe distribution oF survival oF thyroila cancer patients by sex, age QU alagnosis, and vype oF tumor; anc, To establish the distribution of the causes of death as entered on deata certificates of patients previously clagnosed as saving thyroid cancer Summary: The collection of wayeone patrolcey Gata and case histories as collected in Uten acd Nevada from 1946-1963 will be extended to other States including the State or Avizona. Priority will be given to the collection of tnese data rom States in waich populavion svudies referred to above are being performed. Zrfrort will be made to work back Prom known. mortality swavisvics to Cevelop Gata on meroidity/morvality relavicnsnins for vnyroid cancer and vo Cevelop morbidity ata data for 4. TOT Gow roid UVAYPOLG d4iseases aiseases emone “4S am persons 2 uncer “ whiz vy years o2 age.