ef
wnhis new infor.aciion and the reactions and recommene, the Division ot nadiolosical !Eoaztn is programing
0
ms oO
tu
Fu © 4
. 3p
wow
res
20%
rection of its biomedical prozrams to place greater emphasis on
t's
Chg wf & pf.
+
i ad
ey och
@ te
pO
3
NEW AND EXPANDED STUDI"'S ON TINROTD TUMORIGENS
ucies that may clarify the etiologic significance of radiation in the
oduction oF thyroid tumors. However, other program commitments and
u
geucary
aud personnel cellings provide only very limited latitude for
iwpaed
4
irection
SASAy
of
effort.
nV
ana
m
_
ae
Nevada
Test
Sit
surrounding States concerning tne pos
who may also be involved, the Div
ations involved with regard to
tae apprehension existing in
uy OF as yet unknown populations
cho
Recognizing the national policy;
.
5
use oFmi
the
COMee: mued
“Radiological Health is immedia-
po
tely reprogramming its epidemioloz
i and supportive biomedical and environmental programs to place greater envhasis on tne relative significance of
one production of thyroid tumo rs.
However, other program
commitments Cet
4 1a DUudgetary and personnel ceiilings permit only Limited latitude for such ce direction of effort.
TALS amendment would allow furtner expansion of ongoing studies and 4
i
Signicicant erlort in tnose imoortant areas oF epidemiology, retrospective
dosimetry, and the study of environmental goitrogens in the locales of
interest.
Without the amendment requested at
it is probable that definitive
answers will not be round for a period of Five to ten years.
With this
aqrnendment, resolution of t aeoL poruant questions may be expected within a
period of
to Tive year.
TWO
Goals and Program Cosectives
In order to clarity tne etiologic importance of radiation in the
production of thyroid tumors, there shoulda se coordinated and directed
efforts to study various demographic, physiologic and morphologic Factors
concommitantiy with radietion exposure
Accorcgingly, the Tollowing orcad study objectives are prooosed Tor
epiceniologic studies
and, wnere aporopriate, for supportive radiobiologic.
stucies:
(1)
To establish vhe prevalence of morbidity and morvality of thy-
roid abnormalities in selected irradietea ana comparison human population
groups witn concomyitant investigation of ypertinent Tamily and individual
nealtn and environmental Tactors.
(2)
To quantity the relations.ips becwwoen irradiation dose and
aducvion of thyroic
(3)
vunors including the importance of irradiation dose
ueLity, and type of radiation and tissue
.
;
To determine the significance of age at time of exposure of the
tnyroie gland in producing thyroid tuners.