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A large population of genetically uniform mice, 6-12 weeks of age, was
exposed to atomic detonation, and after recording the zortality rates during
the first few weeks after exposure, the animals were transported to Oak Ridge

for study of the delayed effects of irradiation, Radiations from atomic
detonation were composed predoninantly of high energy gama rays, with a
wall component of fast and a still malle fiux of slow neutrons, the

gamma to neutron ratio inereasing with the distance from ground sero.
Small susbers of mice were irradiated beneath lead shields, so as to receive
predominantly neutron radiation.

Survival patterns, shom in Table 1, indicate that the 1Dgy/30 days
was approximately 755 r, with little difference between males and famales.

At one year postirradiation the LDgp had dropped to 733 r for miles and
7L6 vr for femmles.

Significant shortening of the life span resulted fran

doses well beneath the threshold for acute lethality.

This reduction of

longevity, appreciably gretter in fenales, resulted from degenerative and
neoplastic diseases induced or exaggerated by irradiation, as will be disclosed.
The first of the delayed effects noted was cataract, which appesred furing
the third month postirradiation,

Within 90 days after exposure virtually all

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