AAP,
aN
attin
irradiated mice had opacities detectable with the slitelamp.
The rate cf
propresgion of the opacities varied directly with the dose (Chart 1).
Lens
damage was nore severe for 2 given dose of neutrons than for camxparable doses
of ge-ma rays; thus, in cataract. induction approximately 100 rep of neutrons
corresponded to about 650 r of gamma rays (nee = 6.5).
Systenetic studies of the eye disclosed a resarkable change of the iris
consisting of prorressive loss of iris tissue, as illustrated in Fig. 1.
This
process appears to be an abloatropry apparmtly hereditary in this strain, as
mild atrophy of the iris occurred In aging nonirradiated contrels; like
cataract, however, the degree of atrophy was significantly greater following
irradiation, in proportion to the dese.
Greying of the fur saa noted as early as 3 months! pestirradiati on,
progressing with time as a fmetion of the dose (Chart 2).
It varied with
different anatomical regions bot in certain areas was sufficiently weil
correlated with the dose te constituta a simple, though only approximate,
biclogical dosimeter.
DO ARCHIVES