276

R. A. Conard

or increased basophil counts indicative of incipient leukaemia was noted.
An increased incidence of leukaemia has been reported in radiologists (March
1947, Ulrich 1946, Warren 1956), in children receiving therapeutic radiation in
infancy for thymic enlargement (Simpson and Hempelmann 1957), in children
exposed in utero from diagnostic x-ray examinations of the mothers (Stewart,
Webb, Giles and Hewitt 1956), in patients receiving x-irradiation for treatment
of ankylosing spondylitis (Court-Brown and Doll 1957) and in survivors of the
atomic bombs in Japan (Maloney and Kastenbaum 1955). Though the
incidence of leukaemia in the exposed Japanese was significantly increased,
the total incidence was low. Therefore, since the exposed Marshallese population
is small, it does not seem likely that leukaemia will be observed as a result of

their radiation exposure.

2.2.4. Cataracts

During the past five years repeated slit-lamp ophthalmological observations
in the Marshallese revealed no opacities typical of the radiation-induced type.
The induction of opacities of the lens by radiation is a well-established fact
in man. In the Japanese exposed to the atomic bombs, opacities of the lens,
including about 10 severe cataracts, have been observed (Cogan, Martin and
Kimura 1949, Sinsky 1955). Merriam and Focht (1957) on the basis of clinical
cases of radiation-induced opacities calculated that 200 r was the minimum dose
of gamma- or x-radiation resulting in lens opacities. Therefore, the dose of
radiation received by the Marshallese may be too low to result in such changes.
2.2.5. Reproduction
It has long been recognized that reducedfertility may be induced by ionizing
radiation in man byrelatively smali doses, possibly even in the dose range that
the Marshallese received. Transient effects on fertility may have taken place
in this group, but such effects were not observed. Studies such as sperm counts
were not feasible. No amenorrhoea was noted in the exposed women. Birth
rate during the past five years in the exposed group was not reduced and,
if anything, appears to have been higher than in the unexposed comparison
population or in the Marshallese people generally. Therefore, the degree of
sterility that may have been induced was not detectable based on these findings.
A somewhat greater prevalence of miscarriages and still-births has been
noted in the exposed women but, due to the paucity of vital statistics in the
Marshallese and the small number of people involved, the data are not readily
amenable to statistical analyses.
2.2.6. Growth and development
Anthropometric measurements on the Marshallese children have revealed
findings, previously reported (Conard et al. 1957), which were interpreted as

suggestive of a slight lag in growth and developmentin the exposed children

during the first few years after exposure. However, certain inconsistencies in
the ages of the children were found, and the data are being re-evaluated based
on more exact age data obtained during the last survey. The results of this
evaluation are not complete enough to make any statements at this time. Such
an effect would not be inconsistent with the findings of Greulich et al. (1953)

Select target paragraph3