- 33 Laskin, et al, indicate a significant carcinocenic response
in the luna at 1400
of lung tissue?®.

rem, succesting a comparable sensitivity
Geesaman indicates that the tissue revair

time in the lung is of the order of one year’,

It therefore

seems aDprooriate, Sut not necessarily conservative,

to accept

as guidance that tnis enhanced cancer risk occurs when particles
irradiate tne surrounding lune tissue at a dose rate of 1000
rem/yr or more.

.
58
19090 raemn/vear to the Surrounding Lung Tissue
Particle
Activity
ee
{oCi)

Particle Diameter
239...
Prd5

2383..,
Put?

3/4 max initlsczed

(138 alveoli}

0.14

0.3

0.12

1/2 max inflated

( 63 alveoli)

0.07

0.5

0.93

0.02

0.4

0.06

Closest 29 alvacli

id

Laskin,

57/

Geesaman, Donali >., UCPrL-50387, Co. Cit, 3-

33."

Tbid

33
37/
NA
wwe

@2

41,

23.

cit.

=e:
i <4
Jepdees
1°
iOy
Based+.uron sracitic
activity
given
ate
—_- —-e

y

we

”

’

\.

Laniznan
wanaisl,

ll.

teh,
»

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(1)

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