8ey

- 30 -

The work of. Laskin, et al, though not specifically
involving deep respiratory tissue, does demonstrate a source
.
.
49
intensiiveresponse curve for lung tissue
~.

A Ru-106

cylindrical source was implanted in the bronchi of rats,

and

cancers were observed to arise from the bronchial evsithelitun.
(7 percent)

|

he response curve indicates a sudstantial ressonse

even at 0.008 uCi burden, and a slow, anvroximately logaritnanic
increase of tumor incidence over three orcers of masnitude

rate,

Tsmors w2rea

(9.3 u diameter} with saveral microcuries

toservec in

7? of

23

animals.

In

a second

.

oes
Tasgxin,
n

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O

Cerber

@xcerirent Cermser exnosed raz lungs +o Ca-iti sarticles.

.
24/4
.

th

iy
$e
w
ry

wD

19° ves the incitence was acsroximately wro-inirds.
26 glass beats

-accurulated

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rr

eccumula

ws

an

5
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bh

For

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ine

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vrad.

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esa owl
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w

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TAB

For

ve
wegen:
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.
st
tee
a
S., f M. Nusenner, ff “. Nelson, . 3. Altsnuliear, J.B.
it
=
~
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=
=
22
Carcine7s of ina Lunzy in rats amnosad
=:
,
.
.
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5
l
i
OF intra-broncnia
rerinanium--? selilsacs.
on
i
~
ft
7
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”
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.
vrtlitionszicts,"
J.
Rol. Tanter Inst. IL,

TT

tee
~-=
=
a
>
3
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From 2 Rucvrtectated
me
eye 244
>, LEES, op. 9259-532

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