Laskin, et al, indicate a significant carcinogenic response
in the lung at 1400
.
5G
t
.
oss
Gcesainan indicates
lung is of
~
suggesting a comparable sensitivity
-
of lung tissue”™”~.
time in the
rem,
.
“
.
;
the order of cne vear™’.
Rh
;
that the tissue repair
ro
5
7
.It therefore
seems appropriate, but not necessarily conservative, to accept
as guidance that this enhanced cancer risk cccurs when particles
irradiate the
surrounding lung tissue at a dose rate of 1000
rem/yr or more.
TABLE IV
Particle Activity and Size to Give a Dose of
ral
2060 rem/year to the Surrounding Lung Tissue
Particle
Particle Diameter
npc)
239 Bu.
alveoli)
0.14
0.8
0.12
1/2max inflated ( 68 alveoli)
0.07
0.6
0.09
Closest 20 alveoli
0.02
0.4
0.06
3/4
max
intlated
56/
Laskin,
57/
Geesaman,
58/
Ibid
(138
.
et al, Op.
(u)??
238pu0>
cit.
ll.
cit., p.
Donald P., UCRL-50387, Op.
Based upon specific activity given by Langham, W.H.,
59/
Op. cit., p. 7.
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