-10This abortive rise is faisly consistent and apparently has little prosnostic value.
It may last for only 24 hours.
not well understood.
The cause of this abortive rise in leutocytes is
It may be cormpccrablie to the waves of reccnezation and des=
truction that have been described for other organs (Bloom).
above LDcp in docs and swine.
It has not been seen
Various explenstions have been offercd.
Somatic
mutations of precursors that result in abnormal progeny have been ccnsidered (Bloom)
and Jacotson).
These progeny or theic precursors may have shorter life spans.
There is no satisfactory explanation tc date for this phenomenon.
8.6.3
Erythrocytes.
Chanses in the level of the red biood celis are much
less striking in the early period after irradiation in the mid-lethai dose range.
There is little increase during the first few days.
In animals thet survive radia-
tion in tke 0 to 100% lethal ronse there is a definite decrease in the levels of
the red celi count, hematocrit readinss and hemoglobins between the 10th and 30th
days after exposure.
The mosinun dezsee of anemia is usually reached azound the
15th to 20th days in the survivors.
In the animals which do not survive, there is
usually a marked decrease in the red ccld Levecis a day or so before death.
The deo
crease in the red cells are duc to three factors: (1) decrease or cessation of pro=-
duction of red celis; (2) incezecased destruction; (3)
Cronkite, Sciwess ect al.; Davis et ai.}.
rehace (Jacobson et al.;
The occasional macrocytosis thzt is scen
in swine and other gnimals about 10 to 20 days ofter exposuse to a low lcthal dose
is due to a concomitant reticulocytosis occuring es a scesult of recencsation of the
bone moerow with release of large numbers of reticulocytes in the peripheral bicod
(Cronkite).
An increase in the number of the ced celis is uncommon except in the high dose
range, cs was seen at Dikini during the atomic bomd test.
There were some anixmals
that develoned
a marched hemoconcentsction within a few dsys
(fig.
>?
¥ of the exposure
=D
& 4).
This hemoccncentratioa
tion resulting fron cnoreria, diarzhea, etc.
%
Qa
Q
(oz
“S
fr
°o
e
a
t
0
p>
o
The hematocrit of one coat attained a vaine of almost 80%.