--~ 4
Mice...
820
2,100 altogether.
aA
48, 49.
80
.25
1
05
40
16
coc
5
Significant reduction in mean life
duration.
Negligible reduction in mean life duration,
The most extensive experiment on
chronie Sr toxicity.
Tumor la-
tent period appears to vary as
inverse square root of dose.
Dependence of incidence on dose
suggests that each quantity of
absorbed radiation confers on
tissue absorbing it a probability
of tumor formation which ts without limit in time.
Significantly higher tumor incidence
than controls at this andall higher
dose levels.
Humans: x and gama irradiation of bone produce malignant tumors. Incidence apparently low. 11 cases reviewed, mostly 200 KV. x-ray
treatment. In most cases, estimated hone dose about 8,000-10,000 rads. One case about 5,000 rads. Latent period 6-22 years.
I?
onATHOUY g0d
50...
410
160
Meanlife duration about 44 control. .
aE
‘as
“Pape
see) -