7
Le
| Rats.....
6-12 mos,...{
(Con,)
|
!!
,
8 days. ....
|
Carrier [o......0.... ,
free
20% | «2.0... |
12me....-4..000.0..
20%
12mgeg.....
LPL... ell... | Carrier
|
free.
Oral......... Normal 8r/Ca ratio
|
(~ 10-3).
| 8 weeks (iow
P rickets).
Rats..... ) Daily diet
|
from birth.
8 days.....)
9...
Rats..... | Growing... ..
Weeks... ..
Oral. .... 0...
Sr/Ca intake=2.3
1073,
10...)
Rats.....|
Adult. ......
4 days.....
Oral... 22...
O.45 inghoo.... ee,
day,
41-35%
WB fece cece cece,
7a
45%
45%]
8...
2
Months....;
|
!
|
|
l
|
|
0.35
Sr/Ca retained=
5.51074.
0.25
|
Cees |
eae
OS |
....
45 cee eee
45%}
Rats..... | Adalt.......
1dav......
|S Le
O.1—75mgj.....--..... See com-/]
ment.
12...'
Rabbit...]
9days.....)
LV..........
Carrier
6 weeks. ....
free to
0.02 gm
Sr per
rabbit.
6 months....|
9 davs.....
0.9
32% |
13% | 1.5
j........, | Leceeae ;
1i...|
|
|
LV... ...do ...,|
0.02 gm
Ca/day
in diet.
0.2 gm Ca
per day
in diet.
1.3 gm Ca
per day
in diet.
0.04 gm
55%
000... |
000.0,, !
oo. |
.......
.......
bees
Rats in this group on low P
diet, therefore rachitic.
Rats kept on standarddict of
known 8r/Ca ratio throughout life.
Rats kept on standard diet"of
knownSr/Ca ratio throughout period of growth.
| Dose fed for 7 consecutive
!
days, animals sacrificed on
|
8th day.
Sr retention decreased byfactor of only 5 over 750 fold
range of Sr injection.
Amount of Sr carrier had no
influence
on
Sr
retention
within experimental error of
10%. Lffeet of dietary Ca
on Sr retention is apparent,
though data not quantitative since uptake of Ca from
gut is unknown,
46%
31%
5T%
.-...
17%
wees
12%
.......
B%
10...
30%
30%
Ca/day
in diet.
0.4 gm Ca/
13...|
Steer.....
18 months...|
9 days.....
T.V.......0.. 12.d0....,
,
Y year.......
7 days.....
Oral... . 200.
Carrier
free.
|
in
diet.
2 gm Ca/
day in
diet.
0.4 gm Ca/
day in
diet,
|............
Retention computed by subtracting excretion from ad-
1
|
ministration.
Le
oFATHOUE BOD
day
oe
.
ne
ARO, SES Aeeatenryopet
+
:
.
mM
RE Reem be ty
.
ve