SSegesys RRS, 328 RADIATION STANDARDS, INCLUDING FALLOUT Of the 264 persons measured,the followingisa listing of the num- bers in each radium content group. <0.001 microcurie. a 0.001 to 0.01 microcurie. 0.01 to 0.1 microcurie. 0.1 to 1 microcurie______.--___--__--_...-- >1 microcurie Peraons — -- 23 - _a- 36 102 62 41 A total of 164 persons were measured whose radium contents were grouped in order of magnitude below and above the present occupational permissible level of 0.1 microcurie (uc). Of these, 151 were studied radiographically. In the range 0.01 to 0.1 microcurie, 80 out of 90 failed to show bonelesions, 8 had minimal, and 1 lesions of moderate severity. None had advanced lesions or malignancies. Of 62 persons measured in the range of 0.1 to 1 microcurie, 61 were radiographed. Of these, only 25 had no bonelesions; 18 had minimal; 9 mild; 9 moderate; and 5 advanced lesions. In this radium content range, three persons had malignant neoplasms. Above 1 microcurie, 40 of 41 persons measured were radiographed. Of the 40 persons, 28 had advanced bone lesions. Of these, 14 had malignant neoplasms. Only 12 of the 40 persons had lesions of moderate or lesser severity. An analysis of malignant neoplasms has been done both in the present group of persons reported and also in those other radium-bearing patients whom members of our group have had the opportunity to study to somelesser degree. A total of 24 persons developed malignant neoplasms out of approximately 300. In our group the lowest terminal body content at which a malignancy was seen was 0.45 microcurie; the highest, 6.8 microcurie. No myeloid leukemias have been seen in the patients currently under study. A review of death certificates of former dial painters in the Chicago area turned up twolisted as “splenic leukemia” in the early 1930’s. By good fortune we were able to find and study the original blood smears made in 1931 on one of these two patients and are able to confirm the diagnosis of acute myeloid leukemia. The other “splenic leukemia” remains unconfirmed. May I sav parenthetically that in the past when people have talked about the radium dial painters, it has been stated that no leukemias were seen. I think we must now say that we can confirm the presence of one case of myeloid leukemia. Representative Price. Were there any cancer cases found in the radium dial painters? Dr. Hasteruix. Yes,sir. Representative Price. You cover that in your statement? Dr. Hasrerirx. Yes, sir; there is a total of 17 malignancies. Representative Pricr. But it is covered in your statement? Dr. Hasrerrix. Yes, sir. Whatdose-effect relationships can we tentatively draw from these studies? And they are tentative and very rough estimates. In the body content range between 1 and 10 microcuries we have a total of 41 persons with about 1,300 man-years irradiation experience. The probability per man-year of exposure—14 malignancies in this group— is thus about 1.06 times 10*. If we plot our only other point—that of the 2,200 man-years irradiation experience in the 0.1 to 1.0 microcurie IMPRGHEBNEARER osheenha CERgeaE