| | 160|/- T | a | 140 }— a _ 4 a E 130K ~ MEDIAN STATURE % 4 UNEXPOSED BOYS a ~ lad { ax a 7 vt 2 a 2 a - \ = a Sg 7 ! i Woe as ¥ 100— 4 90L- j ~Ww Z THYROID | 1 > — 5 120 a e w | a STATURAL GROWTH SUBJECTS #38 #5 1S0;—- ~i..--L1 28 . i : SKELETAL AGE 3 oO HEIGHT AGE — SUBJECT NO.3 == SUBJECTNOS J HORMONE | = STARTED B0r— 4 l 3 _| 6 ! 9 1 12 CHRONOLOGICAL AGE (YEARS) | 15 Z Figure 31. Relative patterns of statural growth (corre- lated with chronological age) in the two boys who had marked hypothyroidism. Comparison is with unexposed. Note enhanced growth after thyroid treatment. Figure 33. One of the two boys (25) showing most retardation of growth with developmentof hypothyroidism. Left: near the beginning of thyroid hormone treatment(1966, age 13); right: after 3 years of treatment(1969), showing remarkable spurt in growth and development with dissappearance of hypothyroid symptoms. = 8 1 1 iO + THYROID HORMONE STARTED ‘ | 12 ' | t4 F 16 CHRONGLOGICAL AGE { YEARS} Figure 32. Relative patterns ofskeletal maturation (correlated with chronological age) in the two bovs who had marked hypothyroidism. Comparison is with unexposed . boys. Note the dramatic changein slope of growth curves after thyroid hormone administration.