100rr 106 I 60 q x w a w = «sa. Rateé (%) 3 - 60 PROBABILITY > Ke 40 J a = t a ! = 3 e OI 0.01 “9 i! i . re ~ 6 ohn emy 28 4s DECREASE ~ = = 55, 100 INJECTED DOSE (»e/tar ad. | fee. is i, Control f Range | 1000 10,000 , i P Average probability of dying with a malignant hone tumor as a furetion ob isotope dose, Re Hee ee 1 20 . ! 20 ba gr90 ° L 40 IN AVERAGE A 60 i 80 SURVIVAL 100 TIME (%) Figure 5, Figure 4. Pi ! Comparative lethality from bone tumor induction in the CFl female mouse. From Finkel (1953). Comparative lethality of several elements of the beagle dog. Bone tumor development was the primary cause of lethality. The effects are expressed as relative biological effectiveness (RBE) relative to 226Ra. From Dougherty and Mays (1969). 11 10