DOCUMENT SOURCE

Lawrence Berkeley Laboratory
Archives and Records Office

RECORDS SERIES TITLE

Applied Science Divisian: Scientists’ Papers - Papers of William E. Siri
ACCESSION NO.

434-91-0131

FILE CODE NO.

19-14-18

CARTON NO

7

FOLDER NAME

COPY

ACS by

Dr. Leo Meyer (Marshall Island Natives)

NOTES

FOUND BY

Perry Hall

{2

UNIVERSITY OF CALIFORNIA
DONNER LABORATORY AND DONNER PAVILION

May 2 1963

BERKELEY 4, CALIFORNIA

Dear Dr.Meyer,
I received the pipet, the serum samples and
the data on your subjects. I have distilled the serum, and
when cur new scintillation counter is set up I will7the

water sammoles and send you the results. + had all the water
samples monitered in Donner Eab's
whole body cgunter just
to maxe sure they were not contaminated with Cr¢

As far as I can determine,Will hasrit done

any work on the relationship between blood volume and lean
body mass in the four years that I have worked for him.
Nor can I find anything published by anyone at Donner Lab
on this subject.

The most recent article that I know of is by
F.P.Muldowney of Harvard Med. School in"Techniques for

measuring body composition" p 212. I enclose the title, page
of this publication so you can look it up. Muldowney saves
the linear regression of red cell mass(y)
on lean body mass

(x) as

y= 32.74x

Is this

+

155.17

the formula that you are looking for?
Dr. Eoward Parker the Associate Research

Physician at Donner said that about 8 years ago, Will and

others

tried expressing plood volume in terms of og /em of

lean vody wt. rather tnan cc/ gm of total body wt.Theoretic
-ally this snould have sroduced a better correlation, but
after trying a couple

-fF hundred patients this way,

the

researchers decided to go back to “he old method.The €linic
still uses

the old methd.

I will send you the water volumes, the Kgs o

or fat and the lean body mass on your subjects as soon as
possidle.I will also send you my calculations for your file.

We were not able to establish radio contact
as we nad hoped, so we have no news that is-nst in .the news~
caper, The mail

service has also been very poor and we have

had oniy one letter from Will.Al1l he said was that some of
tne scientific equipment has broken down and this is spoil~
ing some of the planned research.
ae
Sincerely

by

}

Rosemary Hughes

P.S.

Please forgive the typing..I'm no typist,

and pecker.

*

1

i

-

just a hunt

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