ome

25 ml alcohol and 63 ml toluene.
background of about 80 c/m.

i=?

The H1IO is detected with 6% efficiency and a

The Na22 efficiency at its much lower gain setting

is 70% with a background again of about 80 c/n.

c

a

Pulse Height Meesurement

Jayes, V,Kerr):

The first three of an expected large number of potential scintillation solutes have been received from Dr. Henry Gilman, Iowa State College, and
tested as 3g/l toluene solutions without further purification.

values obtained were:

tetrabenylfuran, 0.55; N-phenylcarbazole, 0.24; and

P-phenylphenanthridine, 0,03.

d,
D,

Ott,

C,

_

PharmacologyofOxazole Quaternary Salts.

Lushbau

-

The LA RPH

(B. Rogers, N. Hayes,
-

.

|

Investigation of the hypothermic action of tosylate salts of

The salt of 2-(1-naphthyl)-5~phenyloxazole

oxazoles in mice has been continued.

has continued to give the most interesting results,

The following table gives a

typical set of data showing the effect of a dose of 1 mg per 10 g body weight
on the body temperature of mice as a function of time after injection.
Timeafter Injection (min.)

0
Body Temperature

c°

37

__

20°C

40.2

60

100

200

200

400

§00

600

32

28.5

26

25

24

25

29

31.5

33

Toxicity studies have been run on the. salts of several oxazoles and these compared
with similar studies with Thorazine.

Dose response curves have also been determined

on at least three of the more interesting compounds.

Classification changed te

by en oe
Ys
of

a
vee

LAnk 2

3

Per

LheLe saglik

E.R

Lt,Poy

(Perso; ZH
Ly,
iy
smson) (Date)
By
Lge
LY
OoLu/f

(Signgture of person making the change, and date)

DE

Ord

Select target paragraph3