AOL 31
11/24/73
SUMMARY ON ADVICE CONCERNING MNIKK BIKINT ISLANDERS
Brewen and Preston:
Oak Ridge
Logistics: 200 people, 6 per day - would take two people about 1 month
Equipment: Small med lab, 2 portable incubators, centrifuge, microscope
‘People: perhaps 1 person could do it, but two much better
need people of technician level - highly qualified
Carolyn Gooch could do it, Judy Bodicoat (Shelly's assistant) could tox
Siside reading: More than 1 lab might do it
Shelly Wolf
Mike Bender
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Brewen and Preston
"~~ Kastenbaum-~--Amer: -Tob+ Inst--Statistician-and expert on experimental
design
Medical records: Good records needed
Organization: perhaps need an expert panel to get it organized.
Mayall and Carrano:
Lawrence Livermore
Method: Interested in using their technique of measuring total DNA /chromosome
Very sensitive now. looks promising and need a test population to
work it out on.
with age.
Perhaps can see a 2 to 5% difference
Perhaps 18 months until ready to go in field
mitn DNA variation is indeed greater in older people, say in the
BikdidkdGink
content of a specific chromsome.
or gaps
Chromsomal method - loss: let culture go through 2 divisions, which
would show up---as a DNA-loss in-2nd. division.
Blood could be collected in field - delivered to Livermore.
Chromosomes would be stained with usual method and also
banding methods.
Semen samples might also be collected -- Bart Gladhill, reproductive biologist
Johns Hopkins
Shoudd do itt}
Method Blood samples pre-resettlement - somebody in Hawaii could make
slides. Fly blood to Hawaii.
fimmm Slides could be
stored for examination later - should be frozen, but important
to be kept dry '
People: A ¢professional should plan it and decide who whould do it.
farrano - good, but might like to practice first
In house capanility - perhaps faster;
LASL - Peterson, Devin (worked with Brandom)
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Bender: