ERS?

;

NEEL ET AL.

264

RESULTS

i

Polymorphisms
Genetic polymorphisms were observed in six of the systems: haptoglobin, phosphoglucomutase-1, adenosine deaminase, acid phosphatase, 6-phosphoglucose de-

hydrogenase, and group specific component. Phenotype and allele frequencies are
given in table 2, Because of extensive inter-island population movement since the
TABLE 2
Grn FREQUENCIES For Stx GesEtic PotysronpHisiss Iw THE MARSHALL ISLANDS
PeENOTY?E

Adenosine deaminase ........

I
1974
1975

0

324

48

0

114
76

69
81

2
20

190

150

22

1974
1975

56
43

4
87

o31
53

99

181

84

1974

158

25

46

1

4

295

71

5

AEB

B

1974
1975

........ eewenes

Total ...cccccecccccesace

Phosphoglucomutase-It ......

1975

Total ...... cece eeee eae

137

A

Acid phosphatase ............

1974

1975

Total .... 2... ceca eens
6-Phosphogiuconate dehy-

drogenase ..........eceeeee

1974

1975

Total oo. ccc cece een cees

101

73

55

12

221

128

23

164

21

0

344

28

0

7

Gene Frequency

372

ADA! = 935

362

Gel = .732

364

Hpi = S21

371

FGMit == 891

372

ACPA = .766

372

6PGD4 = .962

.

11

120

180

Tora.

0

30

Total .........cceesceees
Haptoglobin*

18

2

137

. Total 2... 2. .eeefa eeeeeen
Group specific component ....

167

z-4

0

* The Hp® type was observed in four individuals,

t Two ezamples of the PGM phenotype 2-7 and 2 single phenotype 1-7 were observed.

Bikini incident, results are not presented separately by island. Varying numbers of

determinations for the systems listed in tables 1 and 2 are due to a considerable time

lapse between collection of the samples and their receipt in the laboratory. As a
consequence, either no pattern or an unclear pattern (even after repetition) was

occasionally obtained for a given trait. Three persons had the PGM; 7 phenotype.
Because of the occurrence of this variant in polymorphic proportions elsewhere in

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