Vol. iss,Ne8, ment ofskin lesions, spotty noted.(fig. 3.4). - the Fs eye oh =P 7 + war are .¥- 7 at: Dee og Te Ue i ht ne ee eee, ' eats particularty around the telangiectatic vessels. Atrophy : AMES" 6k ett 0 abe Eyre og Fig. ET fe Yackefticaip at | sai ft ct amawtRte pestworeen otea edema of the pars papillaris with lymphocytic infiltration, . Cae Oe a Lebar Dea Aa SPI Leake ae were agen <4 ps che, St iS ce any SAT WRN OD SER OIE EDS 5 or preceded by lesions , growthof hairot ‘ioral ‘color kad@iczibition was was completeti toontha’ehesthe cecidiot (i 38). develoving ident: (fig; course as obeorved byKnowlton and oo-orkers +inia- dividualsafter handlingconceptrated fission productsor latent periods before. appearance on different parts of the body and appeared inroughly the: following,s0~ quential order: scalp, neck, axillary region, antecubital fossae, feet, arms, legs, and trunk. The neck and scalp lesions were most common; however, a substantial num- ber of antecubital fossae lesions arid foot lesions were seen. Lesions on the flexor surfaces tended to appear Dereon’ lesionsonextensor surfaces,”‘These differences in tent pe: not appear to be related entirely to the dose to the skin, since severe foot lesions, presumably caused by the foot receiving a larger dose of radiation, did not appear until after other less severe Iesions. The first indication of a lesion was an increase in pigmentation in the form of macules, papules,and raised plaques -(fig. 44). Usually these dark pigmented lesions had a dry,thickened,leathery depigmented to the surrounding skin (fig. 48).: During the next few weeks, the lesions gradually became repigmented and the skin became. normal in. appearance. Ap proximately -20%-:of the: group.developed deeper le- sions.: These were seen on theneck;écalp, andear, and most frequently on the fret (fig. 5 and 6).These lesions. were painful and were characteriztd by wet desquama-. tion with weeping and crusting, and, in. some footle: Follow-up studies at six months and one year showed tion had in most cases disap- ~ that the peared. At the site of deeper footlesions andthe ear lesions, there were pink-to-white areas that had not re- pigmented (fig. 5B). In these areas the skin appeared slightly. atrophic. Treatment of the skin lesions contisted of daily cleansing and symptomatic therapywith